Levonorgestrel and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levonorgestrel (levonorgestrel) and Abilify (aripiprazole). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Levonorgestrel and Abilify. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Levonorgestrel?

Levonorgestrel has active ingredients of levonorgestrel. It is often used in birth control. eHealthMe is studying from 4,186 Levonorgestrel users. Check the latest studies of Levonorgestrel.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,454 Abilify users. Check the latest studies of Abilify.



On Jul, 12, 2026

37 people who take Levonorgestrel and Abilify together, and have interactions are studied.

Levonorgestrel and Abilify drug interactions.

What are the common drug interactions of Levonorgestrel and Abilify, by gender? *:

female:

  1. Anxiety
  2. Chest discomfort
  3. Suicide attempt
  4. Fatigue (feeling of tiredness)
  5. Weight increased
  6. Abortion induced (medically referred abortion)
  7. Abortion spontaneous (naturally occurring miscarriage)
  8. Anion gap decreased
  9. Ankylosing spondylitis (type of arthritis affecting the spine)
  10. Bankruptcy

male:

n/a

What are the common drug interactions of Levonorgestrel and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Anxiety
  2. Chest discomfort
  3. Hypoaesthesia eye (reduced sense of touch or sensation on eyes)
  4. Oropharyngeal discomfort (pain or irritation of oropharynx)
  5. Throat tightness

10-19:

n/a

20-29:

  1. Abortion induced (medically referred abortion)
  2. Anion gap decreased
  3. Bankruptcy
  4. Blood calcium decreased
  5. Blood chloride increased
  6. Blood creatine phosphokinase increased
  7. Blood urea decreased
  8. Carbon dioxide increased
  9. Haematocrit decreased
  10. Haemoglobin decreased

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Balance disorder
  3. Flushing (the warm, red condition of human skin)
  4. Fatigue (feeling of tiredness)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Weight increased
  7. Hypophagia (reduced food intake)
  8. Anxiety
  9. Chest discomfort
  10. Hypoaesthesia eye (reduced sense of touch or sensation on eyes)

40-49:

n/a

50-59:

n/a

60+:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Lung adenocarcinoma (a form of non-small cell lung cancer)
  3. Pregnancy on contraceptive
  4. Urinary tract infection
  5. Venous thrombosis limb (blood clot that forms in a vein in the limb)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 21.62%
  2. Bipolar Disorder (mood disorder): 8 people, 21.62%
  3. Pain: 7 people, 18.92%
  4. Stress And Anxiety: 5 people, 13.51%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 10.81%
  6. Rheumatoid Factor Negative: 4 people, 10.81%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 8.11%
  8. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 8.11%
  9. Borderline Personality Disorder: 3 people, 8.11%
  10. Sleep Disorder: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levonorgestrel and Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levonorgestrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levonorgestrel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levonorgestrel and aripiprazole (the active ingredients of Levonorgestrel and Abilify, respectively), and Levonorgestrel and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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