Levophed and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levophed (norepinephrine bitartrate) and Colace (docusate ). Common drug interactions include insomnia among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Levophed and Colace. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Levophed?

Levophed has active ingredients of norepinephrine bitartrate. eHealthMe is studying from 2,047 Levophed users. Check the latest studies of Levophed.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

On Jul, 17, 2026

77 people who take Levophed and Colace together, and have interactions are studied.

What are the common drug interactions of Levophed and Colace, by gender? *:

female:

Insomnia (sleeplessness)
Asthenia (weakness)
Cardiogenic shock (inadequate circulation of blood)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Mass
Nausea (feeling of having an urge to vomit)
Pericardial effusion (fluid around the heart)
Presyncope
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Tuberculin test positive

male:

Hypotension (abnormally low blood pressure)
Pneumonia
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperkalaemia (damage to or disease of the kidney)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Pulmonary haemorrhage (acute bleeding from the lung)
Sepsis (a severe blood infection that can lead to organ failure and death)
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood lactic acid increased
Blood urea increased

What are the common drug interactions of Levophed and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blood creatinine increased
Blood lactic acid increased
Blood urea increased
Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)

20-29:

Cardiac failure congestive
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholecystitis (infection of gallbladder)
Influenza like illness
Insomnia (sleeplessness)
Urinary tract infection
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Intracardiac thrombus (presence of a circumscribed mass with heart wall)
Mass
Multi-organ failure (multisystem organ failure)

30-39:

Abdominal pain
Confusional state
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Delirium (wild excitement)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Immune system disorder
Leukocytosis (increased white blood cells)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Nausea (feeling of having an urge to vomit)

40-49:

Ileus (a painful obstruction of the ileum or other part of the intestine)
Pneumonia
Septic shock (shock due to blood infection)
Anxiety
Emotional distress
Fear
Injury
Pain
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Fear
Stress
Hypotension (abnormally low blood pressure)
Arthralgia (joint pain)
Asthenia (weakness)
Balance disorder
Brain midline shift
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cerebral haemorrhage (bleeding within the brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

Pneumonia
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dyspnoea (difficult or laboured respiration)
Respiratory failure (inadequate gas exchange by the respiratory system)
Acute respiratory distress syndrome
Asthenia (weakness)
Cardiac failure congestive
Cardiogenic shock (inadequate circulation of blood)
Fungaemia (fungi circulate in the blood)
Injury

What are the existing conditions these people have? *

Pain: 18 people, 23.38%
Multiple Myeloma (cancer of the plasma cells): 14 people, 18.18%
Nausea (feeling of having an urge to vomit): 13 people, 16.88%
High Blood Pressure: 10 people, 12.99%
Hypotension (abnormally low blood pressure): 10 people, 12.99%
Insomnia (sleeplessness): 9 people, 11.69%
Oedema (fluid collection in tissue): 7 people, 9.09%
Nausea And Vomiting: 7 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 7.79%
Dyspnea (difficult or laboured breathing): 6 people, 7.79%

* Approximation only. Some reports may have incomplete information.

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