Levothroid and Folvite drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Folvite (folic acid). Common drug interactions include memory impairment among females and cardiac failure congestive among males.
The phase IV clinical study analyzes what interactions people have when they take Levothroid and Folvite. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Levothroid?
Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.
What is Folvite?
Folvite has active ingredients of folic acid. eHealthMe is studying from 2,529 Folvite users. Check the latest studies of Folvite.
39 people who take Levothroid and Folvite together, and have interactions are studied.

What are the common drug interactions of Levothroid and Folvite, by gender? *:
female:
- Memory impairment
- Myalgia (muscle pain)
- Nervousness
- Oedema (fluid collection in tissue)
- Oedema peripheral (superficial swelling)
- Peripheral swelling
- Photophobia (extreme sensitivity to light)
- Post herpetic neuralgia (neuralgia caused by the varicella zoster virus)
- Renal impairment (severely reduced kidney function)
- Tenderness (pain or discomfort when an affected area is touched)
male:
- Cardiac failure congestive
- International normalised ratio increased
- Influenza
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Pancreatitis chronic (chronic inflammation of pancreas)
- Pyrexia (fever)
- Viral upper respiratory tract infection
- Vomiting
- Alcohol abuse
What are the common drug interactions of Levothroid and Folvite, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Fall
- Headache (pain in head)
- Hypertension (high blood pressure)
- Syncope (loss of consciousness with an inability to maintain postural tone)
50-59:
- Dysarthria (speech disorder)
- Gait disturbance
- Muscular weakness (muscle weakness)
- Neuropathy peripheral (surface nerve damage)
- Spasmodic dysphonia (a voice disorder characterized by involuntary movements or spasms of one or more muscles of the larynx)
- Speech disorder
- Asthenia (weakness)
- Cardiac failure congestive
- Chest discomfort
- Chest pain
60+:
- Liver disorder (liver diseases)
- Pleural effusion (water on the lungs)
- Septic shock (shock due to blood infection)
- Urinary tract infection pseudomonal
- Visual impairment
- Weight decreased
- Blood cholesterol increased
- Blood phosphorus increased
- Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
- Drug effect decreased
What are the existing conditions these people have? *
- Pain: 15 people, 38.46%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 28.21%
- Nausea (feeling of having an urge to vomit): 7 people, 17.95%
- Wheezing (a high-pitched whistling sound made while you breath): 6 people, 15.38%
- Chest Pain: 6 people, 15.38%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.26%
- Headache (pain in head): 4 people, 10.26%
- Sleep Disorder: 4 people, 10.26%
- Diarrhea: 4 people, 10.26%
- Colitis (inflammation of colon): 3 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Levothroid and Folvite?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Levothroid (8,974 reports)
- Folvite (2,529 reports)
Browse all drug interactions of Levothroid and Folvite:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Levothroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Folvite:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Levothroid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Folvite and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on levothyroxine sodium and folic acid (the active ingredients of Levothroid and Folvite, respectively), and Levothroid and Folvite (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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