Levothroid and Herceptin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Herceptin (trastuzumab). Common drug interactions include alopecia among females.

The phase IV clinical study analyzes what interactions people have when they take Levothroid and Herceptin. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Herceptin?

Herceptin has active ingredients of trastuzumab. It is often used in breast cancer. eHealthMe is studying from 42,205 Herceptin users. Check the latest studies of Herceptin.



On Jul, 16, 2026

15 people who take Levothroid and Herceptin together, and have interactions are studied.

Levothroid and Herceptin drug interactions.

What are the common drug interactions of Levothroid and Herceptin, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Dyspnoea (difficult or laboured respiration)
  3. Hair colour changes
  4. Hair disorder
  5. Pain
  6. Peripheral embolism (sudden interruption of blood flow to an organ or body part)
  7. Pleural effusion (water on the lungs)
  8. Psychological trauma
  9. Tachypnoea (a condition of rapid breathing over 20 per minute)
  10. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

male:

n/a

What are the common drug interactions of Levothroid and Herceptin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  2. Alopecia (absence of hair from areas of the body)
  3. Psychological trauma

50-59:

  1. Alopecia (absence of hair from areas of the body)
  2. Cardiac failure
  3. Cardiac failure congestive
  4. Dyspnoea (difficult or laboured respiration)
  5. Ejection fraction decreased (systolic heart failure)
  6. Pleural effusion (water on the lungs)
  7. Tachypnoea (a condition of rapid breathing over 20 per minute)

60+:

  1. Alopecia (absence of hair from areas of the body)
  2. Blood glucose increased
  3. Bone loss
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Device failure
  6. Dyspnoea (difficult or laboured respiration)
  7. Hair colour changes
  8. Hair disorder
  9. Pain
  10. Peripheral embolism (sudden interruption of blood flow to an organ or body part)

What are the existing conditions these people have? *

  1. Breast Cancer Metastatic: 5 people, 33.33%
  2. Nausea (feeling of having an urge to vomit): 3 people, 20.00%
  3. Stress And Anxiety: 2 people, 13.33%
  4. Insomnia (sleeplessness): 2 people, 13.33%
  5. Breast Cancer Female: 2 people, 13.33%
  6. Thyroid Diseases: 1 person, 6.67%
  7. Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
  8. High Blood Pressure: 1 person, 6.67%
  9. Feeling Of Relaxation: 1 person, 6.67%
  10. Diabetes: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and Herceptin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levothroid and Herceptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Herceptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levothroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Herceptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium and trastuzumab (the active ingredients of Levothroid and Herceptin, respectively), and Levothroid and Herceptin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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