Ovral and Bactrim ds drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ovral (ethinyl estradiol; norgestrel) and Bactrim ds (sulfamethoxazole; trimethoprim). Common drug interactions include alanine aminotransferase increased among females.

The phase IV clinical study analyzes what interactions people have when they take Ovral and Bactrim ds. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Ovral?

Ovral has active ingredients of ethinyl estradiol; norgestrel. It is often used in birth control. eHealthMe is studying from 1,571 Ovral users. Check the latest studies of Ovral.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

On Jul, 16, 2026

15 people who take Ovral and Bactrim ds together, and have interactions are studied.

What are the common drug interactions of Ovral and Bactrim Ds, by gender? *:

female:

Alanine aminotransferase increased
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Skin nodule (slightly elevated lesions on or in the skin)
Aortic valve incompetence
Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Eye pain
Mitral valve incompetence (inefficient heart valve)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)

male:

n/a

What are the common drug interactions of Ovral and Bactrim Ds, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Breast discharge
Febrile neutropenia (fever with reduced white blood cells)
Hypertriglyceridaemia (excess of triglycerides in the blood)

20-29:

Alanine aminotransferase increased
Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Hypotension (abnormally low blood pressure)
Vaginal cellulitis (vaginal spreading skin infection)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Skin nodule (slightly elevated lesions on or in the skin)
Febrile neutropenia (fever with reduced white blood cells)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Renal failure (kidney dysfunction)
Electrocardiogram t wave amplitude decreased

30-39:

Body temperature increased
Flushing (the warm, red condition of human skin)
Hyperhidrosis (abnormally increased sweating)
Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

Cardiomyopathy (weakening of the heart muscle)
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Mitral valve incompetence (inefficient heart valve)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sedation
Sinus polyp (abnormal tissue growths that grow inside the nasal passages and sinuses)
Tonsillitis (inflammation of tonsil)
Tricuspid valve incompetence (inefficient heart valve)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 33.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.67%
Haematological Malignancy (cancer that affect blood, bone marrow, and lymph nodes): 1 person, 6.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.67%
Acne (skin problems that cause pimples): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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