Levothroid and Voriconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Levothroid (levothyroxine sodium) and Voriconazole (voriconazole). Common drug interactions include deep vein thrombosis among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Levothroid and Voriconazole. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Levothroid?

Levothroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,974 Levothroid users. Check the latest studies of Levothroid.

What is Voriconazole?

Voriconazole has active ingredients of voriconazole. It is often used in aspergillosis. eHealthMe is studying from 21,706 Voriconazole users. Check the latest studies of Voriconazole.



On Jul, 14, 2026

11 people who take Levothroid and Voriconazole together, and have interactions are studied.

Levothroid and Voriconazole drug interactions.

What are the common drug interactions of Levothroid and Voriconazole, by gender? *:

female:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Pyrexia (fever)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Back pain
  5. Memory impairment
  6. Mobility decreased (ability to move is reduced)
  7. Osteomyelitis (infection of bone)
  8. Phlebitis (inflammation of the walls of a vein)
  9. Speech disorder
  10. Spinal cord abscess (pus in spinal cord)

male:

  1. Acute respiratory failure
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Drug effect decreased
  4. Fungal infection
  5. Haemorrhage (bleeding)
  6. Hypotension (abnormally low blood pressure)
  7. Pneumonia
  8. Pulmonary haemorrhage (acute bleeding from the lung)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)
  10. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)

What are the common drug interactions of Levothroid and Voriconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

50-59:

  1. Local swelling (swelling at the site of some application of substance or injury)
  2. Neck pain
  3. Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
  4. Pyrexia (fever)

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Back pain
  3. Spinal cord abscess (pus in spinal cord)
  4. Weight decreased
  5. Blood calcium decreased
  6. Blood magnesium decreased
  7. Blood potassium decreased
  8. Heart rate increased
  9. Platelet count decreased
  10. Streptococcal sepsis (whole body inflammation by streptococcal)

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 63.64%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 63.64%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 63.64%
  4. Pain: 7 people, 63.64%
  5. Joint Pain: 6 people, 54.55%
  6. Blood Pressure Diastolic Increased: 6 people, 54.55%
  7. Immunodeficiency: 5 people, 45.45%
  8. Streptococcal Infection: 4 people, 36.36%
  9. Multiple Myeloma (cancer of the plasma cells): 4 people, 36.36%
  10. Infection: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Levothroid and Voriconazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Levothroid and Voriconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Levothroid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Voriconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Levothroid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Voriconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on levothyroxine sodium and voriconazole (the active ingredients of Levothroid and Voriconazole, respectively), and Levothroid and Voriconazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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