Lexapro and Adempas drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Adempas (riociguat). Common drug interactions include drug hypersensitivity among females and hospitalisation among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Adempas. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Adempas?

Adempas has active ingredients of riociguat. eHealthMe is studying from 29,741 Adempas users. Check the latest studies of Adempas.



On Jul, 15, 2026

89 people who take Lexapro and Adempas together, and have interactions are studied.

Lexapro and Adempas drug interactions.

What are the common drug interactions of Lexapro and Adempas, by gender? *:

female:

  1. Drug hypersensitivity
  2. Hypoaesthesia (reduced sense of touch or sensation)
  3. Lethargy (tiredness)
  4. Weight decreased
  5. Blindness
  6. Chest discomfort
  7. Drug ineffective
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Hypoacusis (loss of hearing)
  10. Hypoxia (low oxygen in tissues)

male:

  1. Hospitalisation
  2. Pain in extremity
  3. Gastritis (inflammation of stomach)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Hypotension (abnormally low blood pressure)
  6. Ileus (a painful obstruction of the ileum or other part of the intestine)
  7. Weight decreased
  8. Diarrhoea
  9. Fall
  10. Hypersensitivity

What are the common drug interactions of Lexapro and Adempas, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Nausea (feeling of having an urge to vomit)

30-39:

  1. Appendicitis (inflammation of the appendix)
  2. Cardiac failure congestive
  3. Chest pain
  4. Dizziness
  5. Drug hypersensitivity
  6. Dyspnoea (difficult or laboured respiration)
  7. Heart rate increased
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Hospitalisation

40-49:

  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Headache (pain in head)
  4. Hypotension (abnormally low blood pressure)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Nausea (feeling of having an urge to vomit)
  7. Pain in jaw
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pruritus (severe itching of the skin)
  10. Sinus pain

50-59:

  1. Pulmonary congestion (congestion in the lungs)
  2. Suicidal ideation
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Viral infection
  5. Blood potassium increased
  6. Dyspnoea (difficult or laboured respiration)
  7. Anaemia (lack of blood)
  8. Diarrhoea
  9. Headache (pain in head)
  10. Dyspepsia (indigestion)

60+:

  1. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  2. Constipation
  3. Headache (pain in head)
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Hypotension (abnormally low blood pressure)
  6. Lethargy (tiredness)
  7. Pericardial effusion (fluid around the heart)
  8. Pneumonia
  9. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 70 people, 78.65%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 20 people, 22.47%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Adempas:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adempas:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adempas and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and riociguat (the active ingredients of Lexapro and Adempas, respectively), and Lexapro and Adempas (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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