Lexapro and Azor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Azor (amlodipine besylate; olmesartan medoxomil). Common drug interactions include parasomnia among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Azor. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,465 Lexapro users. Check the latest studies of Lexapro.

What is Azor?

Azor has active ingredients of amlodipine besylate; olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 3,922 Azor users. Check the latest studies of Azor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

73 people who take Lexapro and Azor together, and have interactions are studied.

Lexapro and Azor drug interactions.

What are the common drug interactions of Lexapro and Azor, by gender? *:

female:

  1. Parasomnia (sleep disorders that involve abnormal and unnatural movements, behaviours, emotions, perceptions)
  2. Retching (strong involuntary effort to vomit)
  3. Scratch
  4. Somnambulism (sleep walking)
  5. Asthenia (weakness)
  6. Blood corticotrophin increased
  7. Blood creatinine increased
  8. Blood glucose decreased
  9. Blood potassium decreased
  10. Blood uric acid increased

male:

  1. Cough
  2. Nausea (feeling of having an urge to vomit)
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Anaemia (lack of blood)
  5. Aphonia (inability to produce voice)
  6. Balance disorder
  7. Blood pressure diastolic decreased
  8. Blood testosterone increased
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Chest pain

What are the common drug interactions of Lexapro and Azor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Nausea (feeling of having an urge to vomit)
  4. Back pain
  5. Dyspepsia (indigestion)
  6. Biliary colic
  7. Infection
  8. Injury
  9. Pain
  10. Epistaxis (bleed from the nose)

40-49:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Nausea (feeling of having an urge to vomit)
  3. Anaemia (lack of blood)
  4. Chronic kidney disease
  5. Epistaxis (bleed from the nose)
  6. Gastritis (inflammation of stomach)
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  8. Injection site bruising
  9. Injection site pruritus (severe itching at injection site)
  10. Melaena (the passage of black, tarry stools)

50-59:

  1. Skin discolouration (change of skin colour)
  2. Suicidal behaviour
  3. Ulcer haemorrhage (bleeding ulcer)
  4. Chronic kidney disease
  5. Dyspepsia (indigestion)
  6. Renal failure (kidney dysfunction)
  7. Renal injury (kidney injury)
  8. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  9. Arthralgia (joint pain)
  10. Benign breast neoplasm (benign (non-cancerous) tumours of the breast)

60+:

  1. Fatigue (feeling of tiredness)
  2. Chronic kidney disease
  3. Alopecia (absence of hair from areas of the body)
  4. Asthenia (weakness)
  5. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  6. Diarrhoea
  7. Drug ineffective
  8. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  9. Pruritus (severe itching of the skin)
  10. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the existing conditions these people have? *

  1. Stress And Anxiety: 12 people, 16.44%
  2. High Blood Cholesterol: 9 people, 12.33%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 12.33%
  4. Pain: 8 people, 10.96%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 6.85%
  6. Panic Disorder: 5 people, 6.85%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 6.85%
  8. Migraine (headache): 5 people, 6.85%
  9. Acne (skin problems that cause pimples): 5 people, 6.85%
  10. Nausea (feeling of having an urge to vomit): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Azor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and amlodipine besylate; olmesartan medoxomil (the active ingredients of Lexapro and Azor, respectively), and Lexapro and Azor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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