Lexapro and Duexis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Duexis (famotidine; ibuprofen). Common drug interactions include psoriatic arthropathy among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Duexis. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Duexis?

Duexis has active ingredients of famotidine; ibuprofen. It is often used in arthritis. eHealthMe is studying from 1,731 Duexis users. Check the latest studies of Duexis.

On Aug, 04, 2026

40 people who take Lexapro and Duexis together, and have interactions are studied.

What are the common drug interactions of Lexapro and Duexis, by gender? *:

female:

Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Sinusitis (inflammation of sinus)
Upper respiratory tract infection
Hypoaesthesia (reduced sense of touch or sensation)
Pain
Psoriasis (immune-mediated disease that affects the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Arthralgia (joint pain)
Arthropathy
Blood calcium increased

male:

Chronic kidney disease
Back pain
Abdominal distension
Asthma
Blood pressure fluctuation
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dizziness
Feeling drunk
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)

What are the common drug interactions of Lexapro and Duexis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Headache (pain in head)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Osteoporosis (bones weak and more likely to break)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Skin burning sensation
Spinal compression fracture (fracture due to spinal compression on bone)
Stomatitis (inflammation of mucous membrane of mouth)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

30-39:

Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Sinusitis (inflammation of sinus)
Upper respiratory tract infection

40-49:

Arthralgia (joint pain)
Chronic kidney disease
Joint range of motion decreased (disease of joint movement)
Renal failure (kidney dysfunction)
Shoulder operation
Undifferentiated connective tissue disease

50-59:

Pulmonary embolism (blockage of the main artery of the lung)
Chronic kidney disease
Joint swelling
Renal failure (kidney dysfunction)

60+:

Chronic kidney disease
Abdominal distension
Depressed mood
Dizziness
Fall
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Impaired healing
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Type 2 diabetes mellitus
Wound

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 27.50%
Pain: 7 people, 17.50%
Insomnia (sleeplessness): 7 people, 17.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 15.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 15.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.00%
Stress And Anxiety: 4 people, 10.00%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 10.00%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 7.50%
Gastric Ulcer (stomach ulcer): 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

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