Lexapro and Duphalac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Duphalac (lactulose). Common drug interactions include anaemia among females and cerebral infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Duphalac. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Duphalac?

Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.



On Jul, 07, 2026

14 people who take Lexapro and Duphalac together, and have interactions are studied.

Lexapro and Duphalac drug interactions.

What are the common drug interactions of Lexapro and Duphalac, by gender? *:

female:

  1. Anaemia (lack of blood)
  2. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  3. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  4. Dizziness
  5. Drug eruption (adverse drug reaction of the skin)
  6. Eating disorder
  7. Electrocardiogram qt prolonged
  8. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  9. Hepatic failure (liver failure)
  10. Iron deficiency

male:

  1. Cerebral infarction (less blood supply to brain resulting tissue damage)
  2. Death
  3. Diarrhoea
  4. Septic shock (shock due to blood infection)

What are the common drug interactions of Lexapro and Duphalac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pneumonia
  2. Abdominal pain
  3. Anaemia (lack of blood)
  4. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  5. Diarrhoea
  6. Electrocardiogram qt prolonged
  7. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  8. Iron deficiency
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain

30-39:

n/a

40-49:

  1. Drug eruption (adverse drug reaction of the skin)
  2. Pruritus (severe itching of the skin)

50-59:

  1. Abdominal pain
  2. Decreased appetite
  3. Febrile neutropenia (fever with reduced white blood cells)
  4. Nausea (feeling of having an urge to vomit)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Pyrexia (fever)
  7. Stomatitis (inflammation of mucous membrane of mouth)
  8. Vomiting
  9. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

60+:

  1. Cerebral infarction (less blood supply to brain resulting tissue damage)
  2. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  3. Vomiting
  4. Weight decreased
  5. Compression fracture (fracture due to pressure caused by injury)
  6. Death
  7. Fall
  8. Femur fracture
  9. Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
  10. Surgery

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 6 people, 42.86%
  2. Cough: 3 people, 21.43%
  3. Stress And Anxiety: 3 people, 21.43%
  4. Itching: 3 people, 21.43%
  5. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 21.43%
  6. Nausea And Vomiting: 3 people, 21.43%
  7. Electrolyte Imbalance: 2 people, 14.29%
  8. Hepatic Enzyme Increased: 2 people, 14.29%
  9. Headache (pain in head): 2 people, 14.29%
  10. Gastritis (inflammation of stomach): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duphalac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duphalac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and lactulose (the active ingredients of Lexapro and Duphalac, respectively), and Lexapro and Duphalac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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