Lexapro and Melphalan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Melphalan (melphalan). Common drug interactions include blister among females and nausea among males.
The phase IV clinical study analyzes what interactions people have when they take Lexapro and Melphalan. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
What is Melphalan?
Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.
34 people who take Lexapro and Melphalan together, and have interactions are studied.

What are the common drug interactions of Lexapro and Melphalan, by gender? *:
female:
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Hypoxia (low oxygen in tissues)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Acute respiratory distress syndrome
- Agitation (state of anxiety or nervous excitement)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Atrial thrombosis (blood clot that develops in an artery)
- Back pain
male:
- Nausea (feeling of having an urge to vomit)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Osteonecrosis of jaw (death of bone of jaw)
- Chills (felling of cold)
- Febrile neutropenia (fever with reduced white blood cells)
- Atelectasis (partial or complete collapse of the lung)
- Dental caries
- Injury
- Back pain
- Cataract (clouding of the lens inside the eye)
What are the common drug interactions of Lexapro and Melphalan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Adenoma benign (non-cancerous tumour -secreting)
- Adrenal disorder
- Adrenal mass
- Anaemia (lack of blood)
- Anorectal disorder
- Aortic calcification (aortic calcification sign of heart valve disease)
- Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
- B-cell lymphoma (blood cancer affecting b cells)
- Back pain
50-59:
- Blindness
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Mucosal erosion (peeling off of mucous membrane)
- Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
- Pyrexia (fever)
- Rash
- Skin lesion
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Upper airway obstruction
60+:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pyrexia (fever)
- Dyspnoea (difficult or laboured respiration)
- Pleural effusion (water on the lungs)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Asthenia (weakness)
- Atelectasis (partial or complete collapse of the lung)
- Bone disorder
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Confusional state
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 26 people, 76.47%
- Pain: 7 people, 20.59%
- High Blood Pressure: 6 people, 17.65%
- Neuropathy Peripheral (surface nerve damage): 5 people, 14.71%
- Stress And Anxiety: 3 people, 8.82%
- Nausea (feeling of having an urge to vomit): 3 people, 8.82%
- Itching: 3 people, 8.82%
- Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 5.88%
- Sleep Disorder: 2 people, 5.88%
- Nausea And Vomiting: 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Lexapro and Melphalan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lexapro and Melphalan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Melphalan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Melphalan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on escitalopram oxalate and melphalan (the active ingredients of Lexapro and Melphalan, respectively), and Lexapro and Melphalan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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