Lexapro and Mesalamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Mesalamine (mesalamine). Common drug interactions include hypersensitivity among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Lexapro and Mesalamine. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
What is Mesalamine?
Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.
91 people who take Lexapro and Mesalamine together, and have interactions are studied.

What are the common drug interactions of Lexapro and Mesalamine, by gender? *:
female:
- Hypersensitivity
- Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
- Jugular vein thrombosis (clot in jugular vein)
- Ligament sprain (ligament stretched)
- Onychomycosis (fungal infection of the nail)
- Pneumonia
- Rib fracture
- Urinary tract infection
- Uterine disorder
- Vaginal discharge
male:
- Fall
- Chest injury
- Ankle fracture
- Bone density decreased
- Bone loss
- Cerebral haemorrhage (bleeding within the brain)
- Chronic kidney disease
- Concussion (short loss of normal brain function in response to a head injury)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Craniocerebral injury (injury to cranium and brain)
What are the common drug interactions of Lexapro and Mesalamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Alcohol use
- Cerebral haemorrhage (bleeding within the brain)
- Concussion (short loss of normal brain function in response to a head injury)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Craniocerebral injury (injury to cranium and brain)
- Fall
- Joint lock
- Laceration (tearing of soft body tissue)
- Loss of consciousness
- Muscle spasms (muscle contraction)
20-29:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Throat irritation
- Abdominal pain upper
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Diarrhoea
- Dizziness
- Headache (pain in head)
- Infusion related reaction
- Pain
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Pain
- Emotional distress
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Ankle fracture
- Bone density decreased
- Bone loss
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Cough
40-49:
- Nausea (feeling of having an urge to vomit)
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Intracranial venous sinus thrombosis (presence of thrombosis (a blood clot) in the dural venous sinuses, which drain blood from the brain)
- Sinusitis (inflammation of sinus)
- Weight increased
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Breast cyst
- Headache (pain in head)
- Jugular vein thrombosis (clot in jugular vein)
50-59:
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Photophobia (extreme sensitivity to light)
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Pruritus (severe itching of the skin)
- Pyrexia (fever)
- Renal failure acute (rapid kidney dysfunction)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Sensory disturbance (sense disturbance)
- Septic shock (shock due to blood infection)
- Staphylococcal bacteraemia (a bacterial infection of blood)
60+:
- Tooth disorder (tooth disease)
- Insomnia (sleeplessness)
- Uterine disorder
- Arthropod sting (arthropod bite)
- Cellulitis (infection under the skin)
- Drug hypersensitivity
- Fall
- Hypersensitivity
- Infusion site swelling
- Ligament sprain (ligament stretched)
What are the existing conditions these people have? *
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 24 people, 26.37%
- Stress And Anxiety: 11 people, 12.09%
- Immunodeficiency Common Variable: 11 people, 12.09%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 8.79%
- Birth Control: 8 people, 8.79%
- Osteoporosis (bones weak and more likely to break): 6 people, 6.59%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 6.59%
- Nausea (feeling of having an urge to vomit): 5 people, 5.49%
* Approximation only. Some reports may have incomplete information.
Do you take Lexapro and Mesalamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lexapro (91,464 reports)
- Mesalamine (28,053 reports)
Browse all drug interactions of Lexapro and Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Mesalamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Mesalamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on escitalopram oxalate and mesalamine (the active ingredients of Lexapro and Mesalamine, respectively), and Lexapro and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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