Lexapro and Onfi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Onfi (clobazam). Common drug interactions include partial seizures among females and spinal fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Onfi. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Onfi?

Onfi has active ingredients of clobazam. It is often used in epilepsy. eHealthMe is studying from 7,809 Onfi users. Check the latest studies of Onfi.

On Jul, 13, 2026

55 people who take Lexapro and Onfi together, and have interactions are studied.

What are the common drug interactions of Lexapro and Onfi, by gender? *:

female:

Partial seizures (seizures which affect only a part of the brain at onset)
Alopecia (absence of hair from areas of the body)
Diarrhoea
Overdose
Urinary tract infection
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Drug withdrawal convulsions
Fibroadenoma of breast (breast lump)

male:

Spinal fracture (fracture in one of vertebrae)
Mood altered (changes in mood)
Gastroenteritis (inflammation of stomach and intestine)
Hospitalisation
Hunger
Osteoporosis (bones weak and more likely to break)
Pancreatic carcinoma (pancreatic cancer)
Pneumonia
Somnolence (a state of near-sleep, a strong desire for sleep)
Staphylococcal infection (an infection with staphylococcus bacteria)

What are the common drug interactions of Lexapro and Onfi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Mood altered (changes in mood)
Mouth ulceration (mouth ulcers)
Peripheral swelling

10-19:

Diarrhoea
Balance disorder
Fall
Hypophagia (reduced food intake)
Restlessness (not able to rest)
Weight increased
Wrist fracture
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Alopecia (absence of hair from areas of the body)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)

20-29:

Cataplexy (loss of muscle tone accompanied by full conscious awareness)
Insomnia (sleeplessness)
Spinal fracture (fracture in one of vertebrae)
Diarrhoea
Gastroenteritis (inflammation of stomach and intestine)
Muscle twitching
Pancreatic carcinoma (pancreatic cancer)
Pneumonia
Seasonal allergy (allergic condition due to certain season)

30-39:

Somnolence (a state of near-sleep, a strong desire for sleep)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Cardiac arrest
Dehydration (dryness resulting from the removal of water)
Fibroadenoma of breast (breast lump)
Hypoaesthesia (reduced sense of touch or sensation)
Intraductal papilloma of breast (tiny wart-like growth in breast tissue)
Ovarian cyst (fluid filled sac of the ovary)
Overdose
Partial seizures (seizures which affect only a part of the brain at onset)

40-49:

Aura
Eye movement disorder

50-59:

Ear infection
Simple partial seizures (seizures which affect only a small region of the brain)
Alopecia (absence of hair from areas of the body)
Balance disorder
Pain
Death
Hepatic enzyme increased
Vomiting
Upper respiratory tract infection
Urinary tract infection

60+:

n/a

What are the existing conditions these people have? *

Seizures (abnormal excessive or synchronous neuronal activity in the brain): 21 people, 38.18%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 18.18%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 14.55%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 8 people, 14.55%
Partial Seizures (seizures which affect only a part of the brain at onset): 5 people, 9.09%
Thyroid Diseases: 4 people, 7.27%
Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 7.27%
Heart Disease: 4 people, 7.27%
Constipation: 4 people, 7.27%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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