Lexapro and Ramelteon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Ramelteon (ramelteon). Common drug interactions include hot flush among females and enterocolitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Ramelteon. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Ramelteon?

Ramelteon has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 1,387 Ramelteon users. Check the latest studies of Ramelteon.



On Aug, 01, 2026

13 people who take Lexapro and Ramelteon together, and have interactions are studied.

Lexapro and Ramelteon drug interactions.

What are the common drug interactions of Lexapro and Ramelteon, by gender? *:

female:

  1. Hot flush (sudden feelings of heat)
  2. Abdominal discomfort
  3. Abdominal pain
  4. Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
  5. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
  6. Diarrhoea
  7. Dizziness
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Feeling hot

male:

  1. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Abdominal pain upper
  4. Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
  5. Asthenia (weakness)
  6. Constipation
  7. Libido decreased (loss of interest in sex)
  8. Poverty of thought content
  9. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
  10. Urinary tract infection

What are the common drug interactions of Lexapro and Ramelteon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Injection site mass
  2. Injection site reaction

50-59:

n/a

60+:

  1. Renal failure acute (rapid kidney dysfunction)
  2. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  3. Hot flush (sudden feelings of heat)
  4. Hypertension (high blood pressure)
  5. Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
  6. Nephrogenic anaemia (anaemia due to kidney disease)
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Parkinsonian gait (gait exhibited by patients suffering from parkinson's disease)
  9. Perinephric collection (fluid collections surrounding a kidney)
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Malignant Melanoma (skin cancer rises from melancytes): 2 people, 15.38%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
  3. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 7.69%
  4. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 7.69%
  5. Amyloidosis (a tumour within which amyloid is produced): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Ramelteon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ramelteon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ramelteon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and ramelteon (the active ingredients of Lexapro and Ramelteon, respectively), and Lexapro and Ramelteon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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