Lexapro and Riluzole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Riluzole (riluzole). Common drug interactions include drug ineffective among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Lexapro and Riluzole. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
What is Riluzole?
Riluzole has active ingredients of riluzole. It is often used in amyotrophic lateral sclerosis. eHealthMe is studying from 1,621 Riluzole users. Check the latest studies of Riluzole.
14 people who take Lexapro and Riluzole together, and have interactions are studied.

What are the common drug interactions of Lexapro and Riluzole, by gender? *:
female:
- Drug ineffective
- Death
- Disease progression
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Flushing (the warm, red condition of human skin)
- Muscular weakness (muscle weakness)
- Pneumonia
- Therapeutic response unexpected
male:
- Drug ineffective
- Poor quality sleep
- Disease progression
- Dry skin
- Dyspnoea (difficult or laboured respiration)
- Haemoglobin increased
- Oxygen saturation decreased
- Pruritus (severe itching of the skin)
- Rash
- Skin exfoliation (removal of the oldest dead skin cells)
What are the common drug interactions of Lexapro and Riluzole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Disease progression
- Drug ineffective
- Dysphagia (a condition in which swallowing is difficult or painful)
- Muscular weakness (muscle weakness)
50-59:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Drug ineffective
- Pulmonary embolism (blockage of the main artery of the lung)
- Therapeutic response unexpected
60+:
- Death
- Drug ineffective
- Haemoglobin increased
- Oxygen saturation decreased
- Pneumonia
- Pruritus (severe itching of the skin)
- Rash
- Skin exfoliation (removal of the oldest dead skin cells)
- Urinary incontinence (inability to control the flow of urine and involuntary urination)
- Dyspnoea (difficult or laboured respiration)
What are the existing conditions these people have? *
- Sleep Disorder: 2 people, 14.29%
- Muscle Spasms (muscle contraction): 2 people, 14.29%
- High Blood Cholesterol: 2 people, 14.29%
- Stress And Anxiety: 1 person, 7.14%
- Salivary Hypersecretion (excess saliva secretion): 1 person, 7.14%
- Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 1 person, 7.14%
- Pain: 1 person, 7.14%
- Depressive Symptom: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Lexapro and Riluzole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lexapro and Riluzole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Riluzole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Riluzole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on escitalopram oxalate and riluzole (the active ingredients of Lexapro and Riluzole, respectively), and Lexapro and Riluzole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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