Lexapro and Sabril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Sabril (vigabatrin). Common drug interactions include flushing among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Sabril. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Sabril?

Sabril has active ingredients of vigabatrin. eHealthMe is studying from 12,445 Sabril users. Check the latest studies of Sabril.



On Jul, 16, 2026

28 people who take Lexapro and Sabril together, and have interactions are studied.

Lexapro and Sabril drug interactions.

What are the common drug interactions of Lexapro and Sabril, by gender? *:

female:

  1. Flushing (the warm, red condition of human skin)
  2. Lip disorder (disease of lip)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Gallbladder enlargement
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Dizziness
  7. Head discomfort
  8. Hyperhidrosis (abnormally increased sweating)
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Pneumonia

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  3. Overdose
  4. Pancreatic carcinoma (pancreatic cancer)
  5. Pneumonia
  6. Suicidal ideation
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Vision blurred
  9. Abnormal behaviour
  10. Aggression

What are the common drug interactions of Lexapro and Sabril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acne (skin problems that cause pimples)
  2. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  3. Flushing (the warm, red condition of human skin)
  4. Mass
  5. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  6. Rash generalised (rash on most of body parts)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  9. Stomatitis (inflammation of mucous membrane of mouth)
  10. Swelling face

20-29:

  1. Complex partial seizures (epileptic seizure)
  2. Gastroenteritis (inflammation of stomach and intestine)
  3. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  4. Pancreatic carcinoma (pancreatic cancer)
  5. Pneumonia

30-39:

  1. Flushing (the warm, red condition of human skin)
  2. Lip disorder (disease of lip)
  3. Gallbladder enlargement
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  6. Device expulsion
  7. Pain
  8. Vaginal haemorrhage (vaginal bleeding)
  9. Energy increased
  10. Overdose

40-49:

  1. Abnormal behaviour
  2. Aggression
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Muscle twitching

50-59:

  1. Therapeutic response decreased (less preventive response)
  2. Balance disorder
  3. Gait disturbance
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Vision blurred
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Hypersensitivity

60+:

  1. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  2. Erythema (redness of the skin)
  3. Mass
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Rash
  6. Sneezing
  7. Swelling face

What are the existing conditions these people have? *

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 11 people, 39.29%
  2. Complex Partial Seizures (epileptic seizure): 5 people, 17.86%
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 14.29%
  4. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 3 people, 10.71%
  5. Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 10.71%
  6. Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 3 people, 10.71%
  7. Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 2 people, 7.14%
  8. Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 2 people, 7.14%
  9. Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Sabril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sabril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sabril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and vigabatrin (the active ingredients of Lexapro and Sabril, respectively), and Lexapro and Sabril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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