Lexapro and Tambocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Tambocor (flecainide acetate). Common drug interactions include rales among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Tambocor. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.

What is Tambocor?

Tambocor has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,621 Tambocor users. Check the latest studies of Tambocor.



On Aug, 04, 2026

49 people who take Lexapro and Tambocor together, and have interactions are studied.

Lexapro and Tambocor drug interactions.

What are the common drug interactions of Lexapro and Tambocor, by gender? *:

female:

  1. Rales (an abnormal respiratory sound characterized by fine crackles)
  2. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  3. Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
  4. Activities of daily living impaired
  5. Breath sounds
  6. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  7. Abdominal pain upper
  8. Asthenia (weakness)
  9. Blood potassium decreased
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

  1. Asthenia (weakness)
  2. Asthma
  3. Ageusia (loss of taste functions of the tongue)
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Aortic valve incompetence
  7. Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
  8. Arthralgia (joint pain)
  9. Blood glucose increased
  10. Brain natriuretic peptide increased

What are the common drug interactions of Lexapro and Tambocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cardiac disorder
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Abnormal behaviour
  4. Activated partial thromboplastin time prolonged
  5. Areflexia (absence of a reflex)
  6. Balance disorder
  7. Blood sodium decreased
  8. Confusional state
  9. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  10. Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)

30-39:

n/a

40-49:

  1. Pain
  2. Palpitations (feelings or sensations that your heart is pounding or racing)
  3. Panic attack
  4. Pickwickian syndrome (extreme obesity accompanied by sleepiness, hypoventilation, and polycythemia)
  5. Sinusitis (inflammation of sinus)
  6. Cardiac failure congestive
  7. Crying
  8. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  9. Dyspnoea (difficult or laboured respiration)
  10. Ear congestion

50-59:

  1. Haematemesis (vomiting of blood)
  2. Hypophagia (reduced food intake)
  3. International normalised ratio increased

60+:

  1. Fall
  2. Fatigue (feeling of tiredness)
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Chest pain
  5. Constipation
  6. Cough
  7. Disturbance in attention
  8. Drug eruption (adverse drug reaction of the skin)
  9. Dyspnoea (difficult or laboured respiration)
  10. Haemoglobin decreased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 16.33%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 16.33%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 12.24%
  4. Pain: 5 people, 10.20%
  5. Insomnia (sleeplessness): 4 people, 8.16%
  6. Swelling: 3 people, 6.12%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 6.12%
  8. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 6.12%
  9. Heart Rate Increased: 3 people, 6.12%
  10. Bipolar Disorder (mood disorder): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lexapro and Tambocor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lexapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tambocor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lexapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tambocor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate and flecainide acetate (the active ingredients of Lexapro and Tambocor, respectively), and Lexapro and Tambocor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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