Lexapro and Unasyn drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lexapro (escitalopram oxalate) and Unasyn (ampicillin sodium; sulbactam sodium). Common drug interactions include groin pain among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lexapro and Unasyn. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Lexapro?

Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,465 Lexapro users. Check the latest studies of Lexapro.

What is Unasyn?

Unasyn has active ingredients of ampicillin sodium; sulbactam sodium. eHealthMe is studying from 4,474 Unasyn users. Check the latest studies of Unasyn.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

53 people who take Lexapro and Unasyn together, and have interactions are studied.

What are the common drug interactions of Lexapro and Unasyn, by gender? *:

female:

Groin pain
Hip fracture
Hypertension (high blood pressure)
Injury
Joint stiffness
Labyrinthitis (inflammation of the labyrinth or inner ear)
Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
Leukopenia (less number of white blood cells in blood)
Mitral valve sclerosis (thickening and stiffness of the valve)
Monoclonal immunoglobulin present

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Cholecystitis acute (rapid infection of gallbladder)
Cough
Diarrhoea
Drug abuse
Gastroenteritis (inflammation of stomach and intestine)
Haematochezia (passage of stools containing blood)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Lexapro and Unasyn, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Back pain
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Cardiac failure congestive
Coagulopathy (blood's ability to clot is impaired)
Congestive cardiomyopathy (weakening of heart muscle)

30-39:

Cellulitis (infection under the skin)
Chest pain
Nausea (feeling of having an urge to vomit)
Abdominal hernia
Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Body temperature decreased
Bone disorder
Chills (felling of cold)

40-49:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Abdominal hernia
Alopecia (absence of hair from areas of the body)
Bone disorder
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Decreased interest
Dental caries
General physical health deterioration (weak health status)
Hepatic cyst

50-59:

Abdominal discomfort
Adenoma benign (non-cancerous tumour -secreting)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aortic valve sclerosis (narrowing of the aortic valve)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone pain
Cardiac murmur (an heart sound in valve abnormality)
Chills (felling of cold)
Constipation

60+:

Abdominal discomfort
Adenoma benign (non-cancerous tumour -secreting)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cataract (clouding of the lens inside the eye)
Chills (felling of cold)
Comminuted fracture (bone has broken into several pieces)
Compression fracture (fracture due to pressure caused by injury)
Deformity (disfigurement)
Dental caries

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 21 people, 39.62%
Pain: 16 people, 30.19%
Upper Respiratory Tract Infection: 15 people, 28.30%
Restless Leg Syndrome (a powerful urge to move your legs): 15 people, 28.30%
Muscle Spasms (muscle contraction): 15 people, 28.30%
Bone Lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 15 people, 28.30%
Breast Cancer: 12 people, 22.64%
Stress And Anxiety: 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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