Librium and Vitamin e drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Librium (chlordiazepoxide hydrochloride) and Vitamin e (tocopherols and tocotrienols). Common drug interactions include colonic polyp among females and white blood cell count increased among males.

The phase IV clinical study analyzes what interactions people have when they take Librium and Vitamin e. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

36 people who take Librium and Vitamin e together, and have interactions are studied.

Librium and Vitamin e drug interactions.

What are the common drug interactions of Librium and Vitamin E, by gender? *:

female:

Colonic polyp (extra part of colon tissue grow in intestine)
Cystitis (inflammation of the wall of the bladder)
Dermal cyst
Headache (pain in head)
Insomnia (sleeplessness)
Intestinal stenosis (partial obstruction that causes the centre opening of the intestine to become narrower)
Lumbar radiculopathy (radicular pain in the low back and legs)
Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
Ventricular extrasystoles (premature cardiac contraction)
Abdominal distension

male:

White blood cell count increased
Abdominal distension
Chest pain
Choking sensation (feeling of obstruction in respiratory system)
Coma (state of unconsciousness lasting more than six hours)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Discomfort
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Excessive bronchial secretion

What are the common drug interactions of Librium and Vitamin E, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abnormal sleep-related event
Balance disorder
Dizziness
Feeling drunk
Headache (pain in head)
Memory impairment
Nausea (feeling of having an urge to vomit)
Pancreatic necrosis (death of pancreas tissue in pancreas)
Pancreatitis (inflammation of pancreas)
Retching (strong involuntary effort to vomit)

40-49:

n/a

50-59:

Pharyngitis (inflammation of the pharynx, causing a sore throat)
Attention deficit/hyperactivity disorder
Cellulitis orbital (acute spread of infection into the eye socket)
Chills (felling of cold)
Inappropriate affect
Increased activity
Nervousness
Non-cardiac chest pain
Pulmonary congestion (congestion in the lungs)
Swelling face

60+:

Diarrhoea
Dizziness
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cholecystitis acute (rapid infection of gallbladder)
Cholecystitis chronic (long lasting infection of gallbladder)
Contusion (a type of hematoma of tissue in which capillaries)
Hepatic steatosis (fatty liver disease)
Hepatomegaly (abnormal enlargement of the liver)
Hot flush (sudden feelings of heat)
Hypertension (high blood pressure)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 8.33%
Insomnia (sleeplessness): 3 people, 8.33%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 5.56%
Irritable Bowel Syndrome: 2 people, 5.56%
Drowsiness: 2 people, 5.56%
Bipolar Disorder (mood disorder): 2 people, 5.56%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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