Lidoderm and Tradjenta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lidoderm (lidocaine) and Tradjenta (linagliptin). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lidoderm and Tradjenta. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Lidoderm?

Lidoderm has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 10,524 Lidoderm users. Check the latest studies of Lidoderm.

What is Tradjenta?

Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

28 people who take Lidoderm and Tradjenta together, and have interactions are studied.

Lidoderm and Tradjenta drug interactions.

What are the common drug interactions of Lidoderm and Tradjenta, by gender? *:

female:

Chronic kidney disease
Anxiety
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chest pain
Emotional distress
Headache (pain in head)
Myalgia (muscle pain)
Pruritus (severe itching of the skin)
Pyrexia (fever)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)
Personality change
Plasma cell myeloma (cancer that begins in plasma cells)
Rash
Renal haemorrhage (bleeding from kidney)
Respiratory failure (inadequate gas exchange by the respiratory system)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematuria (presence of blood in urine)

What are the common drug interactions of Lidoderm and Tradjenta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Headache (pain in head)
Influenza like illness
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Vomiting

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Insomnia (sleeplessness)
Abnormal behaviour
Anxiety
Blood creatinine increased
Blood pressure increased
Cardiac murmur (an heart sound in valve abnormality)
Chest pain

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cellulitis (infection under the skin)
Cervix carcinoma (cancer of cervix)
Chest pain
Chills (felling of cold)
Cough
Depressed mood
Diarrhoea
Dizziness

What are the existing conditions these people have? *

High Blood Pressure: 12 people, 42.86%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 39.29%
Hypersensitivity: 7 people, 25.00%
High Blood Cholesterol: 6 people, 21.43%
Infection: 6 people, 21.43%
Asthma: 5 people, 17.86%
Insomnia (sleeplessness): 4 people, 14.29%
Stress And Anxiety: 4 people, 14.29%
Depression: 4 people, 14.29%
Weight Loss: 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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