Clopidogrel and Endocarditis - a phase IV clinical study of FDA data
Summary:
Endocarditis is reported as a side effect among people who take Clopidogrel (clopidogrel), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetylsalicylic Acid, and have Deep venous thrombosis.
The phase IV clinical study analyzes which people have Endocarditis when taking Clopidogrel. It is created by eHealthMe based on reports of 91,038 people who have side effects when taking Clopidogrel from the FDA, and is updated regularly.
What is Clopidogrel?
Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.
What is Endocarditis?
Endocarditis (inflammation in heart muscle) is found to be associated with 648 drugs and 824 conditions by eHealthMe. Check the latest studies of Endocarditis.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
91,038 people reported to have side effects when taking Clopidogrel.
Among them, 50 people (0.05%) have Endocarditis.

Among these 50 people:
How long have people been on Clopidogrel when they have Endocarditis? *
- < 1 month: 62.5 %
- 1 - 6 months: 37.5 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Endocarditis when taking Clopidogrel? *
- female: 53.19 %
- male: 46.81 %
What is the age of people who have Endocarditis when taking Clopidogrel? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 6.25 %
- 50-59: 9.38 %
- 60+: 84.38 %
What are other drugs people take besides Clopidogrel? *
- Acetylsalicylic Acid: 9 people, 18.00%
- Apixaban: 8 people, 16.00%
- Xarelto: 7 people, 14.00%
- Heparin: 7 people, 14.00%
- Amlodipine: 6 people, 12.00%
- Metformin: 5 people, 10.00%
- Aspirin: 5 people, 10.00%
- Insulin: 5 people, 10.00%
- Ferrous Fumarate: 4 people, 8.00%
- Mirtazapine: 4 people, 8.00%
What are other side effects people have besides Endocarditis? *
- Cardiac Arrest: 9 people, 18.00%
- Haemorrhage Intracranial (bleeding within the skull): 7 people, 14.00%
- Pulmonary Embolism (blockage of the main artery of the lung): 7 people, 14.00%
- Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 14.00%
- Circulatory Collapse: 6 people, 12.00%
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 5 people, 10.00%
- Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 5 people, 10.00%
- Septic Embolus (a type of embolism that is infected with bacteria): 5 people, 10.00%
- Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 5 people, 10.00%
- Renal Atrophy (wasting of kidney): 5 people, 10.00%
What are the existing conditions these people have? *
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 7 people, 14.00%
- Pain: 5 people, 10.00%
- Constipation: 5 people, 10.00%
- High Blood Cholesterol: 4 people, 8.00%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 8.00%
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 4 people, 8.00%
- Osteoporosis (bones weak and more likely to break): 4 people, 8.00%
- Parkinson's Disease: 4 people, 8.00%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 8.00%
- High Blood Pressure: 4 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Clopidogrel and have Endocarditis?
- Check whether Endocarditis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Clopidogrel:
- Clopidogrel (92,160 reports)
Endocarditis treatments and more:
- Endocarditis (9,259 reports)
How severe was Endocarditis and when was it recovered:
Expand to all the drugs that have ingredients of clopidogrel:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Endocarditis:
- Endocarditis (648 drugs)
Browse all the conditions that are associated with Endocarditis:
- Endocarditis (824 conditions)
Related publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clopidogrel (the active ingredients of Clopidogrel) and Clopidogrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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