Linzess and Clindamycin phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Linzess (linaclotide) and Clindamycin phosphate (clindamycin phosphate). Common drug interactions include malaise among females.

The phase IV clinical study analyzes what interactions people have when they take Linzess and Clindamycin phosphate. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Linzess?

Linzess has active ingredients of linaclotide. It is often used in constipation. eHealthMe is studying from 24,086 Linzess users. Check the latest studies of Linzess.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

21 people who take Linzess and Clindamycin phosphate together, and have interactions are studied.

Linzess and Clindamycin phosphate drug interactions.

What are the common drug interactions of Linzess and Clindamycin Phosphate, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Asthma
Screaming (a long loud piercing cry)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Sleep-related eating disorder (abnormal eating patterns during the night)
Surgery
Tachyphrenia (abnormally rapid mental activity)
Tardive dyskinesia (a disorder that involves involuntary movements)
Tongue disorder (disease of tongue)
Arthralgia (joint pain)

male:

n/a

What are the common drug interactions of Linzess and Clindamycin Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

40-49:

Palpitations (feelings or sensations that your heart is pounding or racing)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Blood pressure decreased
Blood pressure fluctuation
Drug hypersensitivity
Drug intolerance (drug sensitivity)
Gastritis (inflammation of stomach)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Obesity (having too much body fat)

50-59:

Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)

60+:

Blood glucose increased
Fatigue (feeling of tiredness)
Injection site pain
Lung infection
Sinusitis (inflammation of sinus)
White blood cell count decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 57.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 47.62%
Multiple Myeloma (cancer of the plasma cells): 4 people, 19.05%
Drowsiness: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Linzess and Clindamycin phosphate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously