Lipitor and Emsam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Emsam (selegiline). Common drug interactions include headache among females and palpitations among males.

The phase IV clinical study analyzes what interactions people have when they take Lipitor and Emsam. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,048 Lipitor users. Check the latest studies of Lipitor.

What is Emsam?

Emsam has active ingredients of selegiline. It is often used in depression. eHealthMe is studying from 1,875 Emsam users. Check the latest studies of Emsam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

36 people who take Lipitor and Emsam together, and have interactions are studied.

What are the common drug interactions of Lipitor and Emsam, by gender? *:

female:

Headache (pain in head)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Confusional state
Dizziness
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)

male:

Palpitations (feelings or sensations that your heart is pounding or racing)
Therapeutic response unexpected
Chest pain
Cold sweat
Cough
Diarrhoea
Drug ineffective
Drug screen false positive
Dry mouth
Erythema (redness of the skin)

What are the common drug interactions of Lipitor and Emsam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chest pain
Cold sweat
Cough
Diarrhoea
Dry mouth
Excessive masturbation
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Irritability
Memory impairment

50-59:

Application site erythema (redness of the skin at application site)
Application site rash
Blood pressure fluctuation
Drug screen false positive
Erythema (redness of the skin)
Pruritus (severe itching of the skin)

60+:

Headache (pain in head)
Insomnia (sleeplessness)
Myalgia (muscle pain)
Non-cardiac chest pain
Obsessive thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry)
Slow response to stimuli (slow response by nerves)
Somnolence (a state of near-sleep, a strong desire for sleep)
Speech disorder
Abdominal pain upper
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 16.67%
High Blood Pressure: 5 people, 13.89%
Insomnia (sleeplessness): 3 people, 8.33%
Enlarged Prostate: 3 people, 8.33%
Pain: 2 people, 5.56%
Neck Pain: 2 people, 5.56%
Megacolon (a very dilated colon): 2 people, 5.56%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.56%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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