Lipitor and Melphalan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Melphalan (melphalan). Common drug interactions include pain among females and malignant melanoma among males.

The phase IV clinical study analyzes what interactions people have when they take Lipitor and Melphalan. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,050 Lipitor users. Check the latest studies of Lipitor.

What is Melphalan?

Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

44 people who take Lipitor and Melphalan together, and have interactions are studied.

Lipitor and Melphalan drug interactions.

What are the common drug interactions of Lipitor and Melphalan, by gender? *:

female:

Pain
Arthralgia (joint pain)
Intervertebral disc degeneration (spinal disc degeneration)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Osteomyelitis (infection of bone)
Pain in extremity
Dyspnoea (difficult or laboured respiration)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Epistaxis (bleed from the nose)

male:

Malignant melanoma (skin cancer rises from melancytes)
Anaemia (lack of blood)
Hypoaesthesia (reduced sense of touch or sensation)
Iron deficiency anaemia
Platelet count decreased
White blood cell count decreased
Cardiac failure congestive
Confusional state
Fatigue (feeling of tiredness)
Leukopenia (less number of white blood cells in blood)

What are the common drug interactions of Lipitor and Melphalan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Arthralgia (joint pain)
Bone disorder
Deformity (disfigurement)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Fall
Infection
Leukopenia (less number of white blood cells in blood)
Mucosal inflammation (infection of mucous membrane)

50-59:

Decreased interest
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Endocarditis bacterial (an inflammation of the inner layer of the heart by bacterial infection)
Fasciitis (infection of muscle surrounding tissue)
Hypergammaglobulinaemia (elevated levels of gamma globulin)
Hyperviscosity syndrome (a condition in which blood is not able to flow freely through your arteries)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc space narrowing (spinal disc space narrowing)
Joint range of motion decreased (disease of joint movement)

60+:

Malignant melanoma (skin cancer rises from melancytes)
Anaemia (lack of blood)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Plasma cell myeloma (cancer that begins in plasma cells)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dizziness

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 34 people, 77.27%
High Blood Pressure: 8 people, 18.18%
Anaemia (lack of blood): 6 people, 13.64%
Pain: 5 people, 11.36%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 11.36%
Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 11.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.09%
Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 3 people, 6.82%
Hypokalemia (low potassium): 3 people, 6.82%
Constipation: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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