Lipitor and Synthroid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Synthroid (levothyroxine sodium). Common drug interactions include asthenia among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Lipitor and Synthroid. It is created by eHealthMe based on reports of 17,513 people who take the same drugs from the FDA, and is updated regularly.
What is Lipitor?
Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.
What is Synthroid?
Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,198 Synthroid users. Check the latest studies of Synthroid.
17,513 people who take Lipitor and Synthroid together, and have interactions are studied.

What are the common drug interactions of Lipitor and Synthroid, by gender? *
What are the common drug interactions of Lipitor and Synthroid, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Lipitor and Synthroid?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lipitor and Synthroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lipitor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Synthroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lipitor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Synthroid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on atorvastatin calcium and levothyroxine sodium (the active ingredients of Lipitor and Synthroid, respectively), and Lipitor and Synthroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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