Lipitor and Unithroid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lipitor (atorvastatin calcium) and Unithroid (levothyroxine sodium). Common drug interactions include asthenia among females and syncope among males.
The phase IV clinical study analyzes what interactions people have when they take Lipitor and Unithroid. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Lipitor?
Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.
What is Unithroid?
Unithroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 890 Unithroid users. Check the latest studies of Unithroid.
38 people who take Lipitor and Unithroid together, and have interactions are studied.

What are the common drug interactions of Lipitor and Unithroid, by gender? *:
female:
- Asthenia (weakness)
- Anxiety
- Diarrhoea
- Dehydration (dryness resulting from the removal of water)
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Gastroduodenitis (an inflammation of the mucous membrane of the stomach and duodenum)
- Pain
- Palpitations (feelings or sensations that your heart is pounding or racing)
male:
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Diarrhoea
- Abnormal dreams
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Fatigue (feeling of tiredness)
- Hyperglycaemia (high blood sugar)
- Hyperhidrosis (abnormally increased sweating)
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
- White blood cell count decreased
What are the common drug interactions of Lipitor and Unithroid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Hyperglycaemia (high blood sugar)
- Papilloedema (optic disc swelling)
50-59:
- Thrombosis (formation of a blood clot inside a blood vessel)
- Vomiting
- Arrhythmia (irregular heartbeat)
- Asthma
- Blood pressure fluctuation
- Diarrhoea
- Fatigue (feeling of tiredness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Heart rate increased
- Hyperhidrosis (abnormally increased sweating)
60+:
- Asthenia (weakness)
- Diarrhoea
- Urinary tract infection
- Balance disorder
- Gastritis (inflammation of stomach)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Fatigue (feeling of tiredness)
- Gait disturbance
- Chills (felling of cold)
- Fall
What are the existing conditions these people have? *
- Cardiac Disorder: 5 people, 13.16%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 10.53%
- Thyroid Diseases: 3 people, 7.89%
- Quit Smoking: 3 people, 7.89%
- Fatigue (feeling of tiredness): 3 people, 7.89%
- Depression: 3 people, 7.89%
- Type 2 Diabetes: 2 people, 5.26%
- Oedema (fluid collection in tissue): 2 people, 5.26%
- Multiple Myeloma (cancer of the plasma cells): 2 people, 5.26%
- Mania (a state of abnormally elevated or irritable mood): 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Lipitor and Unithroid?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lipitor and Unithroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lipitor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Unithroid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lipitor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Unithroid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
- Proti? D, Balti? S, Stupar N, Pavlov-Dolijanovi? S, Mugo?a S, Todorovi? Z, "A case of myositis with immunological background associated with statin use", Open Medicine, 2014 Oct .
- Goldie MP, "Atorvastatin: a new treatment for periodontal disease?", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on atorvastatin calcium and levothyroxine sodium (the active ingredients of Lipitor and Unithroid, respectively), and Lipitor and Unithroid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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