Lipoic acid and Abraxane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lipoic acid (alpha - lipoic acid) and Abraxane (paclitaxel). Common drug interactions include fatigue among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lipoic acid and Abraxane. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Lipoic acid?

Lipoic acid has active ingredients of alpha - lipoic acid. It is often used in peripheral neuropathy. eHealthMe is studying from 5,920 Lipoic acid users. Check the latest studies of Lipoic acid.

What is Abraxane?

Abraxane has active ingredients of paclitaxel. It is often used in breast cancer metastatic. eHealthMe is studying from 19,196 Abraxane users. Check the latest studies of Abraxane.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

16 people who take Lipoic acid and Abraxane together, and have interactions are studied.

Lipoic acid and Abraxane drug interactions.

What are the common drug interactions of Lipoic Acid and Abraxane, by gender? *:

female:

Fatigue (feeling of tiredness)
Neutropenia (an abnormally low number of neutrophils)
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Device related infection
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Infection
Iron deficiency anaemia
Oesophagitis (inflammation of oesophagus)
Osteonecrosis of jaw (death of bone of jaw)

male:

Dyspnoea (difficult or laboured respiration)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Febrile neutropenia (fever with reduced white blood cells)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the common drug interactions of Lipoic Acid and Abraxane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arthralgia (joint pain)
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Device related infection
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Infection
Iron deficiency anaemia
Neutropenia (an abnormally low number of neutrophils)

50-59:

Arthralgia (joint pain)
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Device related infection
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Infection
Iron deficiency anaemia
Neutropenia (an abnormally low number of neutrophils)

60+:

Small intestinal obstruction (blockage in small intestine)
Dyspnoea (difficult or laboured respiration)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cellulitis staphylococcal (a type of bacteria originated skin soft tissue infection)
Cellulitis streptococcal (deep skin soft tissue infection by bacteria)
Febrile neutropenia (fever with reduced white blood cells)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Neutropenia (an abnormally low number of neutrophils)
Pleural effusion (water on the lungs)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the existing conditions these people have? *

Depression: 8 people, 50.00%
High Blood Pressure: 8 people, 50.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 37.50%
Constipation: 6 people, 37.50%
Joint Pain: 5 people, 31.25%
Back Pain: 5 people, 31.25%
Cough: 5 people, 31.25%
Abdominal Pain Upper: 5 people, 31.25%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 5 people, 31.25%
Ovarian Cancer (cancer of ovary): 5 people, 31.25%

* Approximation only. Some reports may have incomplete information.

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