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Lisinopril and hydrochlorothiazide and Dexilant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril and hydrochlorothiazide (hydrochlorothiazide; lisinopril) and Dexilant (dexlansoprazole). Common drug interactions include skull fracture among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and hydrochlorothiazide and Dexilant. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril and hydrochlorothiazide?

Lisinopril and hydrochlorothiazide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 10,259 Lisinopril and hydrochlorothiazide users. Check the latest studies of Lisinopril and hydrochlorothiazide.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

On Jul, 19, 2026

55 people who take Lisinopril and hydrochlorothiazide and Dexilant together, and have interactions are studied.

Lisinopril and hydrochlorothiazide and Dexilant drug interactions.

What are the common drug interactions of Lisinopril And Hydrochlorothiazide and Dexilant, by gender? *:

female:

  1. Skull fracture
  2. Swelling
  3. Tardive dyskinesia (a disorder that involves involuntary movements)
  4. Type 2 diabetes mellitus
  5. Urinary tract infection
  6. Weight decreased
  7. Weight increased
  8. Chronic kidney disease
  9. Renal failure (kidney dysfunction)
  10. Drug ineffective

male:

  1. Arthralgia (joint pain)
  2. Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
  3. Acute leukaemia (blood cancer)
  4. Anal abscess
  5. Asthenia (weakness)
  6. Cellulitis (infection under the skin)
  7. Chills (felling of cold)
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Dizziness
  10. Drug effect decreased

What are the common drug interactions of Lisinopril And Hydrochlorothiazide and Dexilant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug ineffective
  2. Liver injury
  3. Procedural pain

30-39:

  1. Nausea (feeling of having an urge to vomit)

40-49:

  1. Anxiety
  2. Renal failure (kidney dysfunction)
  3. Chronic kidney disease
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal tubular necrosis (death of kidney tubules)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Dyspnoea (difficult or laboured respiration)
  8. Pyrexia (fever)
  9. Renal hypertension (high blood pressure caused by the kidneys hormonal response)
  10. Abscess (pus)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal tubular necrosis (death of kidney tubules)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Drug ineffective
  6. Epistaxis (bleed from the nose)
  7. Abnormal dreams
  8. Arthralgia (joint pain)
  9. Blood glucose increased
  10. Dizziness

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Drug hypersensitivity
  4. Dyspepsia (indigestion)
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Nausea (feeling of having an urge to vomit)
  8. Papillary thyroid cancer
  9. Injection site pain
  10. Nephrolithiasis (calculi in the kidneys)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 17 people, 30.91%
  2. Pain: 17 people, 30.91%
  3. Stress And Anxiety: 13 people, 23.64%
  4. Depression: 9 people, 16.36%
  5. Nausea (feeling of having an urge to vomit): 8 people, 14.55%
  6. Infection: 8 people, 14.55%
  7. Cardiac Disorder: 8 people, 14.55%
  8. Migraine (headache): 6 people, 10.91%
  9. Insomnia (sleeplessness): 6 people, 10.91%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 10.91%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and hydrochlorothiazide and Dexilant?

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- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lisinopril and hydrochlorothiazide and Dexilant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril and hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dexilant:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lisinopril and hydrochlorothiazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexilant and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; lisinopril and dexlansoprazole (the active ingredients of Lisinopril and hydrochlorothiazide and Dexilant, respectively), and Lisinopril and hydrochlorothiazide and Dexilant (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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