Lisinopril and Exalgo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril (lisinopril) and Exalgo (hydromorphone hydrochloride). Common drug interactions include eye movement disorder among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and Exalgo. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Exalgo?

Exalgo has active ingredients of hydromorphone hydrochloride. It is often used in chronic pain. eHealthMe is studying from 9,847 Exalgo users. Check the latest studies of Exalgo.

On Jul, 16, 2026

44 people who take Lisinopril and Exalgo together, and have interactions are studied.

Lisinopril and Exalgo drug interactions.

What are the common drug interactions of Lisinopril and Exalgo, by gender? *:

female:

Eye movement disorder
Fall
Feeding disorder (when children refuse to eat certain food groups)
Feeling jittery
Fluid imbalance (imbalance of fluid in body in intake and fluid lost)
Gastric disorder (disease of stomach)
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Gastroenteritis (inflammation of stomach and intestine)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrointestinal injury (injury to gastrointestinal tract)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Oedema (fluid collection in tissue)
Pulmonary infarction (death of a small area of lung)
Renal failure acute (rapid kidney dysfunction)
Diarrhoea
Nausea (feeling of having an urge to vomit)
Nephrogenic anaemia (anaemia due to kidney disease)
Nephrolithiasis (calculi in the kidneys)
Vomiting

What are the common drug interactions of Lisinopril and Exalgo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cellulitis (infection under the skin)

40-49:

Drug ineffective
Back pain
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Cough
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Oxygen saturation decreased
Speech disorder
Urinary incontinence (inability to control the flow of urine and involuntary urination)

50-59:

Diarrhoea
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fatigue (feeling of tiredness)
Feeling jittery
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Injection site pruritus (severe itching at injection site)
Injection site reaction
Injection site vesicles (fluid- or air-filled cavity or sac at injection site)
Insomnia (sleeplessness)

60+:

Drug ineffective
Renal failure (kidney dysfunction)
Anxiety
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Asthenia (weakness)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block (heart block)
Back pain
Blood creatinine increased

What are the existing conditions these people have? *

Depression: 18 people, 40.91%
Stress And Anxiety: 16 people, 36.36%
High Blood Cholesterol: 15 people, 34.09%
Diabetes: 13 people, 29.55%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 29.55%
Muscle Spasms (muscle contraction): 11 people, 25.00%
Restless Leg Syndrome (a powerful urge to move your legs): 11 people, 25.00%
Nausea (feeling of having an urge to vomit): 11 people, 25.00%
Insomnia (sleeplessness): 10 people, 22.73%
Cough: 10 people, 22.73%

* Approximation only. Some reports may have incomplete information.

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