Lisinopril and Sofosbuvir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril (lisinopril) and Sofosbuvir (sofosbuvir). Common drug interactions include hepatocellular carcinoma among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and Sofosbuvir. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Sofosbuvir?

Sofosbuvir has active ingredients of sofosbuvir. eHealthMe is studying from 9,194 Sofosbuvir users. Check the latest studies of Sofosbuvir.

On Jul, 12, 2026

72 people who take Lisinopril and Sofosbuvir together, and have interactions are studied.

Lisinopril and Sofosbuvir drug interactions.

What are the common drug interactions of Lisinopril and Sofosbuvir, by gender? *:

female:

Hepatocellular carcinoma (liver cancer)
Hyperkalaemia (damage to or disease of the kidney)
Hypophagia (reduced food intake)
Insomnia (sleeplessness)
Leukopenia (less number of white blood cells in blood)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Myositis (inflammation of the muscles)
Pain of skin

male:

Chronic kidney disease
Fatigue (feeling of tiredness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective
Abdominal distension
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone density decreased

What are the common drug interactions of Lisinopril and Sofosbuvir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Hepatitis c rna increased
Hypophagia (reduced food intake)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)

40-49:

Blood testosterone decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Polyuria (production of too much dilute urine)
Vomiting
Abdominal pain
Anaemia (lack of blood)

50-59:

Drug ineffective
Diarrhoea
Nausea (feeling of having an urge to vomit)
Overdose
Anaemia (lack of blood)
Cardiac arrest
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Vision blurred

60+:

General physical health deterioration (weak health status)
Renal impairment (severely reduced kidney function)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Chest pain
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Crying
Depression
Disturbance in attention

What are the existing conditions these people have? *

Hepatitis C: 48 people, 66.67%
Hepatocellular Carcinoma (liver cancer): 10 people, 13.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 12.50%
Hiv Infection: 7 people, 9.72%
Pain: 5 people, 6.94%
Depression: 4 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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