Lisinopril and Sprintec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril (lisinopril) and Sprintec (ethinyl estradiol; norgestimate). Common drug interactions include injury among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and Sprintec. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Sprintec?

Sprintec has active ingredients of ethinyl estradiol; norgestimate. It is often used in birth control. eHealthMe is studying from 4,397 Sprintec users. Check the latest studies of Sprintec.

On Jul, 20, 2026

98 people who take Lisinopril and Sprintec together, and have interactions are studied.

Lisinopril and Sprintec drug interactions.

What are the common drug interactions of Lisinopril and Sprintec, by gender? *:

female:

Injury
Loss of consciousness
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Multiple allergies (allergy to multiple agents)
Oropharyngeal pain
Pneumonia
Pruritus (severe itching of the skin)
Retching (strong involuntary effort to vomit)
Sinus pain
Spinal pain (pain in spine)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Back pain
Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Limb injury
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Plasma cell myeloma (cancer that begins in plasma cells)
Post-traumatic stress disorder
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Lisinopril and Sprintec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Thirst
Abdominal pain lower
Back pain
Escherichia infection (bacterial infection by escherichia coli)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Heart rate increased

20-29:

Abnormal weight gain
Abortion spontaneous (naturally occurring miscarriage)
Acute sinusitis
Alloimmunisation (alloimmunity is an immune response to foreign antigens (alloantigens) from members of the same species)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Bankruptcy
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

30-39:

Fatigue (feeling of tiredness)
Urinary tract infection
Asthenia (weakness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Chest pain
Nasal discomfort
Nasal dryness (dry nose)
Pain
Pulmonary function test decreased
Respiratory syncytial virus infection (viral disease of respiratory system)

40-49:

Ulcer
Urinary tract infection
Urticaria (rash of round, red welts on the skin that itch intensely)
White blood cell count decreased
Balance disorder
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Anxiety
Cough
General physical health deterioration (weak health status)

50-59:

Cystitis (inflammation of the wall of the bladder)
Fatigue (feeling of tiredness)
Hot flush (sudden feelings of heat)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Nausea (feeling of having an urge to vomit)

60+:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Back pain
Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Limb injury
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Plasma cell myeloma (cancer that begins in plasma cells)
Post-traumatic stress disorder
Pulmonary embolism (blockage of the main artery of the lung)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 23 people, 23.47%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 14.29%
Cystic Fibrosis (disease of the secretary glands): 11 people, 11.22%
Pain: 9 people, 9.18%
Nausea (feeling of having an urge to vomit): 8 people, 8.16%
Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 7.14%
Depression: 7 people, 7.14%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 7.14%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 6 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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