Lisinopril and Thiola drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril (lisinopril) and Thiola (tiopronin). Common drug interactions include orthostatic hypotension among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and Thiola. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Thiola?

Thiola has active ingredients of tiopronin. eHealthMe is studying from 1,842 Thiola users. Check the latest studies of Thiola.



On Jul, 13, 2026

15 people who take Lisinopril and Thiola together, and have interactions are studied.

Lisinopril and Thiola drug interactions.

What are the common drug interactions of Lisinopril and Thiola, by gender? *:

female:

  1. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  2. Rash
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Drug ineffective
  5. Fatigue (feeling of tiredness)
  6. Nephrolithiasis (calculi in the kidneys)

male:

  1. Drug ineffective
  2. Cystine urine present
  3. Fatigue (feeling of tiredness)
  4. Abdominal pain
  5. Frequent bowel movements
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Lisinopril and Thiola, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug ineffective

30-39:

  1. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  2. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  3. Rash
  4. Drug ineffective
  5. Abdominal pain
  6. Fatigue (feeling of tiredness)

40-49:

  1. Drug ineffective

50-59:

  1. Drug ineffective
  2. Frequent bowel movements
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Drug ineffective
  2. Cystine urine present
  3. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Cystinuria (formation of cystine stones in the kidneys, ureter, and bladder): 11 people, 73.33%
  2. Seasonal Allergy (allergic condition due to certain season): 1 person, 6.67%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 6.67%
  4. Joint Pain: 1 person, 6.67%
  5. Insomnia (sleeplessness): 1 person, 6.67%
  6. Drowsiness: 1 person, 6.67%
  7. Diabetes: 1 person, 6.67%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.67%
  9. Bladder Spasm: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and Thiola?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lisinopril and Thiola:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Thiola:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lisinopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thiola and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril and tiopronin (the active ingredients of Lisinopril and Thiola, respectively), and Lisinopril and Thiola (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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