Lisinopril and Uniphyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lisinopril (lisinopril) and Uniphyl (theophylline). Common drug interactions include dyspnoea among females and injection site pain among males.

The phase IV clinical study analyzes what interactions people have when they take Lisinopril and Uniphyl. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Lisinopril?

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 358,654 Lisinopril users. Check the latest studies of Lisinopril.

What is Uniphyl?

Uniphyl has active ingredients of theophylline. eHealthMe is studying from 3,086 Uniphyl users. Check the latest studies of Uniphyl.



On Jul, 11, 2026

31 people who take Lisinopril and Uniphyl together, and have interactions are studied.

Lisinopril and Uniphyl drug interactions.

What are the common drug interactions of Lisinopril and Uniphyl, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Dehydration (dryness resulting from the removal of water)
  3. Abdominal pain upper
  4. Asthenia (weakness)
  5. Blood glucose decreased
  6. Chest pain
  7. Drug ineffective
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Pain
  10. Pain in extremity

male:

  1. Injection site pain
  2. Psoriasis (immune-mediated disease that affects the skin)
  3. Faecal incontinence (a lack of control over passing stool)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Hyperglycaemia (high blood sugar)
  6. Hyperkalaemia (damage to or disease of the kidney)
  7. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  8. Mesenteric vascular insufficiency (insufficient vascular supply to mesenteric)
  9. Oedema peripheral (superficial swelling)
  10. Rash macular (small, flat red spots)

What are the common drug interactions of Lisinopril and Uniphyl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Pruritus (severe itching of the skin)
  2. Headache (pain in head)
  3. Injection site discomfort
  4. Injection site erythema (redness at injection site)
  5. Injection site haemorrhage (bleeding from injection site)
  6. Chest discomfort
  7. Vomiting

40-49:

  1. Type 2 diabetes mellitus
  2. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  3. Hyperglycaemia (high blood sugar)
  4. Blood glucose decreased
  5. Cholecystitis acute (rapid infection of gallbladder)
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Comminuted fracture (bone has broken into several pieces)
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Diabetes mellitus inadequate control

50-59:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anaphylactic reaction (serious allergic reaction)
  3. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  4. Nasal dryness (dry nose)
  5. Vision blurred
  6. Apparent life threatening event (an acute, unexpected change in an infant's breathing behaviour that is frightening to the caretaker)
  7. Oropharyngeal pain

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Asthenia (weakness)
  3. Pain in extremity
  4. Stomach discomfort (pain in abdomen)
  5. Sweating increased (excess sweating)
  6. Swelling
  7. Visual disturbance
  8. Vomiting
  9. Blood glucose increased
  10. Bone pain

What are the existing conditions these people have? *

  1. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 22.58%
  2. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 4 people, 12.90%
  3. Asthma: 4 people, 12.90%
  4. Stress And Anxiety: 3 people, 9.68%
  5. Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 9.68%
  6. Pain: 3 people, 9.68%
  7. Osteoporosis (bones weak and more likely to break): 3 people, 9.68%
  8. Ill-Defined Disorder: 3 people, 9.68%
  9. Diabetes: 3 people, 9.68%
  10. High Blood Cholesterol: 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Lisinopril and Uniphyl?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lisinopril and Uniphyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lisinopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Uniphyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lisinopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Uniphyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril and theophylline (the active ingredients of Lisinopril and Uniphyl, respectively), and Lisinopril and Uniphyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: