Lithium carbonate and Suboxone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lithium carbonate (lithium carbonate) and Suboxone (buprenorphine hydrochloride; naloxone hydrochloride). Common drug interactions include injury among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Lithium carbonate and Suboxone. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Lithium carbonate?

Lithium carbonate has active ingredients of lithium carbonate. It is often used in bipolar disorder. eHealthMe is studying from 25,651 Lithium carbonate users. Check the latest studies of Lithium carbonate.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.

On Jul, 19, 2026

44 people who take Lithium carbonate and Suboxone together, and have interactions are studied.

Lithium carbonate and Suboxone drug interactions.

What are the common drug interactions of Lithium Carbonate and Suboxone, by gender? *:

female:

Injury
Insomnia (sleeplessness)
Intentional self-injury
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Joint swelling
Loss of employment
Migraine (headache)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)

male:

Tremor (trembling or shaking movements in one or more parts of your body)
Loss of consciousness
Injury
Psychotic disorder
Tardive dyskinesia (a disorder that involves involuntary movements)
Blood thyroid stimulating hormone increased
Drug dependence
Headache (pain in head)
Salivary gland calculus (stone in salivary gland)
Suicidal ideation

What are the common drug interactions of Lithium Carbonate and Suboxone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Hyperhidrosis (abnormally increased sweating)
Loss of consciousness
Tremor (trembling or shaking movements in one or more parts of your body)
Diplopia (double vision)
Flat affect (absence of emotional response to a situation)
Incontinence (lack of moderation or self-control)
Photophobia (extreme sensitivity to light)

30-39:

Arthralgia (joint pain)
Synovial cyst (cyst of joint filled with synovial fluid)
Tardive dyskinesia (a disorder that involves involuntary movements)
Weight increased
Pneumonia
Weight decreased
Abasia (inability to walk)
Back pain
Bone density decreased
Chest pain

40-49:

Hallucination (an experience involving the perception of something not present)
Psychotic disorder
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Abasia (inability to walk)
Aphasia (damage to the parts of the brain that control language)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

50-59:

Fatigue (feeling of tiredness)
Hypoaesthesia (reduced sense of touch or sensation)
Infusion site bruising
Injection site mass
Joint swelling
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Bradycardia (abnormally slow heart action)
Hypotension (abnormally low blood pressure)
Pulse pressure decreased
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 36.36%
Drug Dependence: 9 people, 20.45%
Stress And Anxiety: 7 people, 15.91%
Depression: 7 people, 15.91%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 13.64%
Drowsiness: 5 people, 11.36%
Insomnia (sleeplessness): 3 people, 6.82%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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