Locoid and Zolpidem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Locoid (hydrocortisone butyrate) and Zolpidem (zolpidem tartrate). Common drug interactions include chest discomfort among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Locoid and Zolpidem. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Locoid?

Locoid has active ingredients of hydrocortisone butyrate. eHealthMe is studying from 1,996 Locoid users. Check the latest studies of Locoid.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

On Jul, 31, 2026

77 people who take Locoid and Zolpidem together, and have interactions are studied.

What are the common drug interactions of Locoid and Zolpidem, by gender? *:

female:

Chest discomfort
Dry mouth
Hypertension (high blood pressure)
Intercostal neuralgia (inflammation of the intercostal nerves)
Iron deficiency anaemia
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Sinusitis (inflammation of sinus)
Uterine leiomyoma (uterine benign tumour derived from smooth muscle)
White blood cell count increased
Abdominal discomfort

male:

Anaemia (lack of blood)
Neuropathy peripheral (surface nerve damage)
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood creatinine increased
Conjunctival hyperaemia (congestion of conjunctival vessels)
Constipation
Gamma-glutamyltransferase increased
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)

What are the common drug interactions of Locoid and Zolpidem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cerebral haemorrhage (bleeding within the brain)
Pancreatitis (inflammation of pancreas)
Sepsis (a severe blood infection that can lead to organ failure and death)
Death
Dizziness
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Vomiting

30-39:

Abdominal pain
Acne (skin problems that cause pimples)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Beta 2 microglobulin increased
Blood albumin decreased
Blood potassium decreased
Chest discomfort
Diarrhoea
Dry mouth

40-49:

Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bacteraemia (presence of bacteria in the blood)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Oedema (fluid collection in tissue)
Panic disorder
Right ventricular failure (right half of the heart fails to work)
Febrile neutropenia (fever with reduced white blood cells)
Blood creatinine increased
Conjunctival hyperaemia (congestion of conjunctival vessels)

50-59:

Diplegia (paralysis of corresponding parts on both sides of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Hypokalaemic syndrome (serum concentration of potassium <3.5)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inflammation
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nuclear magnetic resonance imaging brain
Papillary thyroid cancer
Vasculitis (inflammation of a blood vessel or blood vessels)
Anaemia (lack of blood)

60+:

Diarrhoea
Alanine aminotransferase increased
Generalised oedema (swelling all over the body)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Injection site erythema (redness at injection site)
Oesophageal rupture (break in oesophagus)
Pleural effusion (water on the lungs)
Relapsing fever (bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea)
Spinal compression fracture (fracture due to spinal compression on bone)

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 27.27%
Constipation: 20 people, 25.97%
Rashes (redness): 18 people, 23.38%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 15 people, 19.48%
Pain: 14 people, 18.18%
Diarrhea: 12 people, 15.58%
Stress And Anxiety: 11 people, 14.29%
Febrile Neutropenia (fever with reduced white blood cells): 11 people, 14.29%
Fever: 10 people, 12.99%
Pneumonia: 10 people, 12.99%

* Approximation only. Some reports may have incomplete information.

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