Loperamide hydrochloride and Ezetimibe drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loperamide hydrochloride (loperamide hydrochloride) and Ezetimibe (ezetimibe). Common drug interactions include rheumatoid arthritis among females and pneumonitis among males.

The phase IV clinical study analyzes what interactions people have when they take Loperamide hydrochloride and Ezetimibe. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Loperamide hydrochloride?

Loperamide hydrochloride has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 10,814 Loperamide hydrochloride users. Check the latest studies of Loperamide hydrochloride.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.



On Jul, 18, 2026

55 people who take Loperamide hydrochloride and Ezetimibe together, and have interactions are studied.

Loperamide hydrochloride and Ezetimibe drug interactions.

What are the common drug interactions of Loperamide Hydrochloride and Ezetimibe, by gender? *:

female:

  1. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  2. Rib fracture
  3. Urinary tract infection
  4. Vomiting
  5. Weight decreased
  6. Abdominal discomfort
  7. Anaemia (lack of blood)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

  1. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  2. Pneumonia
  3. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  4. Muscle spasms (muscle contraction)
  5. Neurodegenerative disorder (progressive loss of structure or function of neurons and death of neuron)
  6. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  7. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  8. Respiratory distress (difficulty in breathing)
  9. White blood cell count decreased
  10. Abdominal pain

What are the common drug interactions of Loperamide Hydrochloride and Ezetimibe, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Abdominal discomfort
  2. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  3. Weight decreased

30-39:

n/a

40-49:

n/a

50-59:

  1. Acute myocardial infarction (acute heart attack)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Aphasia (damage to the parts of the brain that control language)
  4. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  5. Fine motor delay (delayed movements and actions of the muscles)
  6. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  7. Muscle spasms (muscle contraction)
  8. Neurodegenerative disorder (progressive loss of structure or function of neurons and death of neuron)
  9. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  10. Abdominal pain

60+:

  1. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  2. Pneumonia
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Decreased appetite
  5. Fatigue (feeling of tiredness)
  6. Ileus (a painful obstruction of the ileum or other part of the intestine)
  7. Lung infection
  8. Nausea (feeling of having an urge to vomit)
  9. Neuropathy peripheral (surface nerve damage)
  10. Streptococcal infection

What are the existing conditions these people have? *

  1. Hyperlipidaemia (presence of excess lipids in the blood): 32 people, 58.18%
  2. High Blood Pressure: 30 people, 54.55%
  3. Cough: 26 people, 47.27%
  4. Constipation: 25 people, 45.45%
  5. Back Pain: 24 people, 43.64%
  6. Dry Mouth: 22 people, 40.00%
  7. Stable Angina (a constant chest pain): 22 people, 40.00%
  8. Thrombocytopenia (decrease of platelets in blood): 22 people, 40.00%
  9. Insomnia (sleeplessness): 22 people, 40.00%
  10. Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 22 people, 40.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loperamide hydrochloride and Ezetimibe:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loperamide hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ezetimibe:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loperamide hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ezetimibe and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride and ezetimibe (the active ingredients of Loperamide hydrochloride and Ezetimibe, respectively), and Loperamide hydrochloride and Ezetimibe (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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