Lopid and Cyclophosphamide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lopid (gemfibrozil) and Cyclophosphamide (cyclophosphamide). Common drug interactions include dizziness among females and alanine aminotransferase increased among males.
The phase IV clinical study analyzes what interactions people have when they take Lopid and Cyclophosphamide. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Lopid?
Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.
What is Cyclophosphamide?
Cyclophosphamide has active ingredients of cyclophosphamide. It is often used in multiple myeloma. eHealthMe is studying from 185,240 Cyclophosphamide users. Check the latest studies of Cyclophosphamide.
18 people who take Lopid and Cyclophosphamide together, and have interactions are studied.

What are the common drug interactions of Lopid and Cyclophosphamide, by gender? *:
female:
- Dizziness
- Dyspepsia (indigestion)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Ejection fraction decreased (systolic heart failure)
- Emotional distress
- Escherichia sepsis (bacterial infection by escherichia coli)
- Exostosis (formation of new bone on the surface of a bone)
- Exposed bone in jaw
- Face oedema (swelling of face)
male:
- Alanine aminotransferase increased
- Anaemia (lack of blood)
- Dizziness
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haemodilution (increase in the volume of plasma in relation to red blood cells)
- Laboratory test abnormal
- Lymphoma (cancer that begins in immune system cells)
- Nausea (feeling of having an urge to vomit)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumonia
What are the common drug interactions of Lopid and Cyclophosphamide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Adverse event
- Angioedema (rapid swelling of the dermis)
- Disease recurrence
- Laboratory test abnormal
- Lymphoma (cancer that begins in immune system cells)
- Pneumonia
- Pruritus generalised (generalized itching)
- Thrombocytopenia (decrease of platelets in blood)
- Urticaria (rash of round, red welts on the skin that itch intensely)
50-59:
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Electrocardiogram st segment depression
- Hyperhidrosis (abnormally increased sweating)
- Hypokalaemia (low potassium)
- Mitral valve incompetence (inefficient heart valve)
- Nausea (feeling of having an urge to vomit)
- Neutropenia (an abnormally low number of neutrophils)
- Pain
- Pco2 decreased
60+:
- Anaemia (lack of blood)
- Diarrhoea
- Asthenia (weakness)
- Back pain
- Carotid artery stenosis (narrowing of carotid artery)
- Chest pain
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Dizziness
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
What are the existing conditions these people have? *
- Interleukin Level Increased: 3 people, 16.67%
- Febrile Neutropenia (fever with reduced white blood cells): 3 people, 16.67%
- Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 3 people, 16.67%
- Breast Cancer: 3 people, 16.67%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 11.11%
- Anaplastic Large Cell Lymphoma T- And Null-Cell Types (t-cell or null-cell cancer, a type of blood cancer): 2 people, 11.11%
- Poor Quality Sleep: 1 person, 5.56%
- Occipital Neuralgia (a condition characterized by chronic pain in the upper neck): 1 person, 5.56%
- Neoplasm Malignant (cancer tumour): 1 person, 5.56%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Lopid and Cyclophosphamide?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lopid (9,700 reports)
- Cyclophosphamide (185,240 reports)
Browse all drug interactions of Lopid and Cyclophosphamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lopid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cyclophosphamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lopid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cyclophosphamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
- Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on gemfibrozil and cyclophosphamide (the active ingredients of Lopid and Cyclophosphamide, respectively), and Lopid and Cyclophosphamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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