Lopid and Nitro-dur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lopid (gemfibrozil) and Nitro-dur (nitroglycerin). Common drug interactions include weight increased among females and rhabdomyolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Lopid and Nitro-dur. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Lopid?

Lopid has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 9,700 Lopid users. Check the latest studies of Lopid.

What is Nitro-dur?

Nitro-dur has active ingredients of nitroglycerin. eHealthMe is studying from 2,414 Nitro-dur users. Check the latest studies of Nitro-dur.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

26 people who take Lopid and Nitro-dur together, and have interactions are studied.

What are the common drug interactions of Lopid and Nitro-Dur, by gender? *:

female:

Weight increased
Anaphylactic reaction (serious allergic reaction)
Anuria (failure of the kidneys to produce urine)
Bone pain
Cardiac disorder
Cardiac enzymes increased
Chest pain
Chest pressure sensation (feeling of pressure on chest)
Chills (felling of cold)
Colitis (inflammation of colon)

male:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Renal failure (kidney dysfunction)
Abdominal distension
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Bulimia nervosa (eating disorder characterized by recurrent binge eating, followed by compensatory behaviours)

What are the common drug interactions of Lopid and Nitro-Dur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiomegaly (increased size of heart than normal)
Cardiovascular disorder (heart diseases)
Chest pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Depression
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Discomfort
Drug maladministration
Dry skin

40-49:

Anxiety
Apnoea (suspension of external breathing)
Bradycardia (abnormally slow heart action)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Gasping (laboured breathing)
Gastro-oesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypopnoea (decrease in the breathing rate)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

50-59:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Cough
Palpitations (feelings or sensations that your heart is pounding or racing)
Paralysis

60+:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Sepsis (a severe blood infection that can lead to organ failure and death)
Anaphylactic reaction (serious allergic reaction)
Anuria (failure of the kidneys to produce urine)
Arthralgia (joint pain)
Chills (felling of cold)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)

What are the existing conditions these people have? *

High Blood Pressure: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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