Lopurin and Panadol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lopurin (allopurinol) and Panadol (acetaminophen). Common drug interactions include pancreatitis among females and pyrexia among males.
The phase IV clinical study analyzes what interactions people have when they take Lopurin and Panadol. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Lopurin?
Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.
What is Panadol?
Panadol has active ingredients of acetaminophen. eHealthMe is studying from 607 Panadol users. Check the latest studies of Panadol.
22 people who take Lopurin and Panadol together, and have interactions are studied.

What are the common drug interactions of Lopurin and Panadol, by gender? *:
female:
- Pancreatitis (inflammation of pancreas)
- Pyrexia (fever)
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Abdominal pain
- Alanine aminotransferase increased
- Amylase increased
- Anaemia (lack of blood)
- Blood potassium increased
- Blood pressure increased
- Cholecystitis (infection of gallbladder)
male:
- Pyrexia (fever)
- Decreased appetite
- C-reactive protein increased
- Limb injury
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hypomania (a mild form of mania, marked by elation and hyperactivity)
- Nosocomial infection (infection from hospital)
What are the common drug interactions of Lopurin and Panadol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Alanine aminotransferase increased
- Amylase increased
- Blood potassium increased
- Pain
- Pancreatitis (inflammation of pancreas)
- Pneumonia
40-49:
n/a
50-59:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Pyrexia (fever)
60+:
- Pyrexia (fever)
- Fatigue (feeling of tiredness)
- Limb injury
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Abdominal pain
- Anaemia (lack of blood)
- Blood pressure increased
- Cholecystitis (infection of gallbladder)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
What are the existing conditions these people have? *
- Constipation: 12 people, 54.55%
- Nausea (feeling of having an urge to vomit): 12 people, 54.55%
- Insomnia (sleeplessness): 8 people, 36.36%
- High Blood Pressure: 7 people, 31.82%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 31.82%
- Multiple Myeloma (cancer of the plasma cells): 7 people, 31.82%
- Asthma: 7 people, 31.82%
- Pneumonia: 7 people, 31.82%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 31.82%
- Fever: 7 people, 31.82%
* Approximation only. Some reports may have incomplete information.
Do you take Lopurin and Panadol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lopurin and Panadol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lopurin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Panadol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lopurin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Panadol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on allopurinol and acetaminophen (the active ingredients of Lopurin and Panadol, respectively), and Lopurin and Panadol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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