Lopurin and Ribasphere drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lopurin (allopurinol) and Ribasphere (ribavirin). Common drug interactions include anaemia among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Lopurin and Ribasphere. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Lopurin?
Lopurin has active ingredients of allopurinol. It is often used in gout. eHealthMe is studying from 190,798 Lopurin users. Check the latest studies of Lopurin.
What is Ribasphere?
Ribasphere has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 9,336 Ribasphere users. Check the latest studies of Ribasphere.
32 people who take Lopurin and Ribasphere together, and have interactions are studied.

What are the common drug interactions of Lopurin and Ribasphere, by gender? *:
female:
- Anaemia (lack of blood)
- Asthenia (weakness)
- Alopecia (absence of hair from areas of the body)
- Depression
- Dizziness postural
- Fatigue (feeling of tiredness)
- Insomnia (sleeplessness)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Oral infection
- Tooth disorder (tooth disease)
male:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Abdominal discomfort
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Blood glucose decreased
- Depression
- Dyspnoea exertional (breathlessness or shortness of breath)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Insomnia (sleeplessness)
What are the common drug interactions of Lopurin and Ribasphere, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Asthenia (weakness)
- Alopecia (absence of hair from areas of the body)
- Depression
- Dizziness postural
- Fatigue (feeling of tiredness)
- Insomnia (sleeplessness)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anaemia (lack of blood)
- Oral infection
- Tooth disorder (tooth disease)
50-59:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Pruritus (severe itching of the skin)
- Anaemia (lack of blood)
- Depression
- Diarrhoea
- Dizziness
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Myalgia (muscle pain)
60+:
- Fatigue (feeling of tiredness)
- Blood glucose decreased
- Vomiting
- Abdominal discomfort
- Dizziness
- Dizziness postural
- Headache (pain in head)
- Influenza like illness
- Insomnia (sleeplessness)
- Pyrexia (fever)
What are the existing conditions these people have? *
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Lopurin and Ribasphere?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lopurin (190,798 reports)
- Ribasphere (9,336 reports)
Browse all drug interactions of Lopurin and Ribasphere:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lopurin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ribasphere:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lopurin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ribasphere and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
- Lin SY, Lin CL, Ju SW, Wang IK, Lin CC, Lin CH, Hsu WH, Liang JA, "Increasing risk of cataract in HCV patients receiving anti-HCV therapy: A nationwide cohort study", PloS one, 2017 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on allopurinol and ribavirin (the active ingredients of Lopurin and Ribasphere, respectively), and Lopurin and Ribasphere (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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