Loratadine and Norflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loratadine (loratadine) and Norflex (orphenadrine citrate). Common drug interactions include acanthoma among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Loratadine and Norflex. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Loratadine?

Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.

What is Norflex?

Norflex has active ingredients of orphenadrine citrate. It is often used in muscle spasms. eHealthMe is studying from 1,951 Norflex users. Check the latest studies of Norflex.

On Jul, 18, 2026

15 people who take Loratadine and Norflex together, and have interactions are studied.

Loratadine and Norflex drug interactions.

What are the common drug interactions of Loratadine and Norflex, by gender? *:

female:

Acanthoma (a skin cancer)
Arthralgia (joint pain)
Atrioventricular block complete (heart block complete)
Blood iron increased
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Cervical cyst (mucus-filled cyst on the surface of the cervix)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Coronary artery stenosis (narrowing of coronary artery)

male:

Chronic kidney disease
Pelvic haematoma (collection of blood outside of a blood vessel in pelvic region)
Renal failure (kidney dysfunction)

What are the common drug interactions of Loratadine and Norflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cholecystitis chronic (long lasting infection of gallbladder)
Injury
Pain

30-39:

Accident at work
Headache (pain in head)
Intervertebral disc protrusion (spinal disc protrusion)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Spinal column injury (spinal cord bone injury)

40-49:

Acanthoma (a skin cancer)
Arthralgia (joint pain)
Atrioventricular block complete (heart block complete)
Blood iron increased
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Carotid bruit (sound heard over the carotid artery area during auscultation)
Cervical cyst (mucus-filled cyst on the surface of the cervix)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Coronary artery stenosis (narrowing of coronary artery)

50-59:

Chronic kidney disease
Pelvic haematoma (collection of blood outside of a blood vessel in pelvic region)
Renal failure (kidney dysfunction)

60+:

Blood glucose increased

What are the existing conditions these people have? *

Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 20.00%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 13.33%
Pain: 2 people, 13.33%
Headache (pain in head): 1 person, 6.67%
Birth Control: 1 person, 6.67%
Blood Pressure Abnormal: 1 person, 6.67%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.67%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 6.67%
Cough: 1 person, 6.67%
Depression: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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