Loraz and Desferal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Desferal (deferoxamine mesylate). Common drug interactions include osteonecrosis of jaw among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Desferal. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,695 Loraz users. Check the latest studies of Loraz.

What is Desferal?

Desferal has active ingredients of deferoxamine mesylate. It is often used in iron overload. eHealthMe is studying from 2,248 Desferal users. Check the latest studies of Desferal.



On Aug, 10, 2026

13 people who take Loraz and Desferal together, and have interactions are studied.

Loraz and Desferal drug interactions.

What are the common drug interactions of Loraz and Desferal, by gender? *:

female:

  1. Osteonecrosis of jaw (death of bone of jaw)
  2. Osteosclerosis (an elevation in bone density)
  3. Pain
  4. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Parapsoriasis (chronic dermatosis of unknown origin, with erythematous , papular, and scaling lesions appearing in)
  7. Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
  8. Pleural effusion (water on the lungs)
  9. Pneumonia
  10. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

male:

  1. Cough
  2. Respiratory tract infection
  3. Chills (felling of cold)
  4. Decreased appetite
  5. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  6. Extrasystoles
  7. Heart rate increased
  8. Joint swelling
  9. Leukocytosis (increased white blood cells)
  10. Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Loraz and Desferal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Cough
  2. Respiratory tract infection
  3. Sinusitis (inflammation of sinus)
  4. Ulcer

20-29:

  1. Liver disorder (liver diseases)
  2. Serum ferritin increased
  3. Blood creatinine increased
  4. Blood phosphorus decreased
  5. Blood potassium decreased
  6. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)

30-39:

  1. Headache (pain in head)
  2. Abdominal distension
  3. Abdominal pain
  4. Acute respiratory failure
  5. Alopecia (absence of hair from areas of the body)
  6. Anaemia of malignant disease
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Asthenia (weakness)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Back pain

40-49:

n/a

50-59:

n/a

60+:

  1. Pyrexia (fever)
  2. Altered state of consciousness (altered state of mind)
  3. Chills (felling of cold)
  4. Drug intolerance (drug sensitivity)
  5. Fatigue (feeling of tiredness)
  6. Gait disturbance
  7. Myalgia (muscle pain)
  8. Retching (strong involuntary effort to vomit)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Vomiting

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 3 people, 23.08%
  2. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 3 people, 23.08%
  3. Respiratory Tract Infection: 3 people, 23.08%
  4. Itching: 2 people, 15.38%
  5. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  6. Cough: 2 people, 15.38%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 15.38%
  8. Anaemia (lack of blood): 2 people, 15.38%
  9. Nausea And Vomiting: 2 people, 15.38%
  10. Pain: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Loraz and Desferal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Loraz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Desferal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Loraz and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Desferal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and deferoxamine mesylate (the active ingredients of Loraz and Desferal, respectively), and Loraz and Desferal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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