Propofol and Prochlorperazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propofol (propofol) and Prochlorperazine (prochlorperazine). Common drug interactions include haematocrit decreased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Propofol and Prochlorperazine. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,225 Propofol users. Check the latest studies of Propofol.

What is Prochlorperazine?

Prochlorperazine has active ingredients of prochlorperazine. It is often used in nausea. eHealthMe is studying from 14,632 Prochlorperazine users. Check the latest studies of Prochlorperazine.



On Aug, 10, 2026

68 people who take Propofol and Prochlorperazine together, and have interactions are studied.

Propofol and Prochlorperazine drug interactions.

What are the common drug interactions of Propofol and Prochlorperazine, by gender? *:

female:

  1. Haematocrit decreased
  2. Leukopenia (less number of white blood cells in blood)
  3. Multi-organ failure (multisystem organ failure)
  4. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Oral candidiasis (fungal infection of mouth)
  6. Pain
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Urinary tract infection
  9. Confusional state
  10. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

male:

  1. Asthenia (weakness)
  2. Chest discomfort
  3. Heart rate increased
  4. Impaired work ability
  5. Oropharyngeal discomfort (pain or irritation of oropharynx)
  6. Oropharyngeal pain
  7. Performance status decreased
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Speech disorder
  10. Vision blurred

What are the common drug interactions of Propofol and Prochlorperazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Groin infection (infection in groin)
  3. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Soft tissue infection
  6. Anal abscess
  7. Anxiety
  8. Depression
  9. Febrile neutropenia (fever with reduced white blood cells)
  10. Genital abscess (build up of pus in genital)

30-39:

  1. Asthenia (weakness)
  2. Chest discomfort
  3. Dyspnoea (difficult or laboured respiration)
  4. Hyperventilation
  5. Cardiovascular disorder (heart diseases)
  6. Chest pain
  7. Flatulence (flatus expelled through the anus)
  8. Heart rate increased
  9. Impaired work ability
  10. Oropharyngeal discomfort (pain or irritation of oropharynx)

40-49:

  1. Mastitis (inflammation of breast)
  2. Anaemia (lack of blood)
  3. Leukopenia (less number of white blood cells in blood)
  4. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Breast cancer stage ii
  7. Breast cellulitis (spreading, acute inflammation of beast skin)
  8. Breast enlargement
  9. Breast haematoma (blood-filled swelling in the breast)
  10. Cerebral venous thrombosis (clot in brains venous blood system)

50-59:

  1. Renal tubular necrosis (death of kidney tubules)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  4. Abdominal pain
  5. Abdominal pain upper
  6. Acidosis (build-up of carbon dioxide in the blood)
  7. Agitation (state of anxiety or nervous excitement)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Aphasia (damage to the parts of the brain that control language)

60+:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Asthenia (weakness)
  3. Fatigue (feeling of tiredness)
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Hypophagia (reduced food intake)
  6. Lethargy (tiredness)
  7. Liver abscess (pus in liver)
  8. Pain
  9. Perihepatic abscess
  10. Pneumobilia (presence of gas in the biliary system)

What are the existing conditions these people have? *

  1. Pain: 13 people, 19.12%
  2. Anaesthesia: 12 people, 17.65%
  3. Constipation: 10 people, 14.71%
  4. Stress And Anxiety: 7 people, 10.29%
  5. Depression: 7 people, 10.29%
  6. Nausea And Vomiting: 6 people, 8.82%
  7. Insomnia (sleeplessness): 6 people, 8.82%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.82%
  9. Type 2 Diabetes: 5 people, 7.35%
  10. Fever: 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Propofol and Prochlorperazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propofol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prochlorperazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propofol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prochlorperazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on propofol and prochlorperazine (the active ingredients of Propofol and Prochlorperazine, respectively), and Propofol and Prochlorperazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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