Loraz and Isturisa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Isturisa (osilodrostat phosphate). Common drug interactions include fatigue among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Isturisa. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.

What is Isturisa?

Isturisa has active ingredients of osilodrostat phosphate. eHealthMe is studying from 1,085 Isturisa users. Check the latest studies of Isturisa.

On Jul, 09, 2026

26 people who take Loraz and Isturisa together, and have interactions are studied.

What are the common drug interactions of Loraz and Isturisa, by gender? *:

female:

Fatigue (feeling of tiredness)
Nasopharyngitis (inflammation of the nasopharynx)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Urinary tract infection
Visual impairment
Iodine deficiency
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting
Asthenia (weakness)
Headache (pain in head)

male:

Fatigue (feeling of tiredness)
Hypertrichosis (hair growth on the body in an amount considered abnormal)

What are the common drug interactions of Loraz and Isturisa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthenia (weakness)
Headache (pain in head)
Iodine deficiency
Nausea (feeling of having an urge to vomit)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting

60+:

Asthenia (weakness)
Blood creatinine decreased
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Urinary tract infection
Visual impairment
Blood pressure increased
Blood sodium decreased
Dizziness
Ear infection
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 18 people, 69.23%
High Blood Pressure: 10 people, 38.46%
Cushing's Syndrome (obesity, a rounded face, increased fat): 8 people, 30.77%
High Blood Cholesterol: 7 people, 26.92%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 6 people, 23.08%
Anaemia (lack of blood): 5 people, 19.23%
Insomnia (sleeplessness): 5 people, 19.23%
Nausea (feeling of having an urge to vomit): 4 people, 15.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 15.38%
Diarrhea: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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