Loraz and Salagen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Loraz (lorazepam) and Salagen (pilocarpine hydrochloride). Common drug interactions include breast cancer among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Loraz and Salagen. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Loraz?

Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,695 Loraz users. Check the latest studies of Loraz.

What is Salagen?

Salagen has active ingredients of pilocarpine hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,966 Salagen users. Check the latest studies of Salagen.

On Aug, 02, 2026

55 people who take Loraz and Salagen together, and have interactions are studied.

What are the common drug interactions of Loraz and Salagen, by gender? *:

female:

Breast cancer
Cardiac murmur (an heart sound in valve abnormality)
Cataract (clouding of the lens inside the eye)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
Constipation
Decreased appetite
Diarrhoea
Drug hypersensitivity

male:

Back pain
Headache (pain in head)
Heart rate decreased
Infusion related reaction
Mouth ulceration (mouth ulcers)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Oral herpes (viral infection of mouth)
Pain in extremity

What are the common drug interactions of Loraz and Salagen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Drug ineffective
Fungal infection
Gastrointestinal motility disorder (abnormal intestinal contractions)
Headache (pain in head)
Hiv test positive
Impaired gastric emptying
Malaise (a feeling of general discomfort or uneasiness)
Mucosal discolouration (change in colour of mucosal membrane)

40-49:

Surgery

50-59:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nausea (feeling of having an urge to vomit)
Oropharyngeal pain
Back pain
Blood pressure fluctuation
Blood pressure increased
Blood uric acid increased
Diarrhoea
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)

60+:

Urinary tract infection
Renal impairment (severely reduced kidney function)
Blindness unilateral
Blood glucose increased
Blood urine present
Cardiac disorder
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 34.55%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 30.91%
Pain: 3 people, 5.45%
Dry Mouth: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

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