Lorazepam and Dantrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorazepam (lorazepam) and Dantrium (dantrolene sodium). Common drug interactions include blood pressure increased among females and cerebral haematoma among males.

The phase IV clinical study analyzes what interactions people have when they take Lorazepam and Dantrium. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Dantrium?

Dantrium has active ingredients of dantrolene sodium. eHealthMe is studying from 1,408 Dantrium users. Check the latest studies of Dantrium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

23 people who take Lorazepam and Dantrium together, and have interactions are studied.

Lorazepam and Dantrium drug interactions.

What are the common drug interactions of Lorazepam and Dantrium, by gender? *:

female:

  1. Blood pressure increased
  2. Cystitis haemorrhagic (blood in the urine and painful voiding)
  3. Depression
  4. Drug hypersensitivity
  5. Muscle tightness
  6. Pain
  7. Drug ineffective
  8. Haematocrit decreased
  9. Asthenia (weakness)
  10. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)

male:

  1. Cerebral haematoma (collection of blood in brain)
  2. Cerebral haemorrhage (bleeding within the brain)
  3. Vomiting
  4. Death
  5. Depressed level of consciousness
  6. Dysarthria (speech disorder)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Facial palsy (paralysis of face nerve)
  9. Neurological symptom (symptoms of nervous system disease)
  10. Oesophageal spasm (contraction of oesophagus)

What are the common drug interactions of Lorazepam and Dantrium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Oesophageal spasm (contraction of oesophagus)
  3. Pleural effusion (water on the lungs)
  4. Vomiting

20-29:

  1. Application site erythema (redness of the skin at application site)
  2. Application site pain
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  5. Drug ineffective
  6. Hypertension (high blood pressure)
  7. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pneumonia
  10. Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)

30-39:

  1. Liver disorder (liver diseases)
  2. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Aspartate aminotransferase increased
  4. Depressed mood
  5. Hepatitis acute
  6. Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
  7. Tolerance increased

40-49:

n/a

50-59:

  1. Cystitis haemorrhagic (blood in the urine and painful voiding)
  2. Haematocrit decreased
  3. Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
  4. Cystitis interstitial (unknown cause characterized by bladder pain)
  5. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
  6. Haemoglobin decreased
  7. Culture urine positive
  8. Drug ineffective
  9. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  10. Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue)

60+:

  1. Asthenia (weakness)
  2. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  3. Facial palsy (paralysis of face nerve)
  4. Neurological symptom (symptoms of nervous system disease)
  5. Diarrhoea
  6. Neoplasm progression (growth of tumour)
  7. Cerebral haematoma (collection of blood in brain)
  8. Cerebral haemorrhage (bleeding within the brain)
  9. Death
  10. Depressed level of consciousness

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 21.74%
  2. Sleep Disorder: 3 people, 13.04%
  3. Insomnia (sleeplessness): 3 people, 13.04%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 13.04%
  5. Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lorazepam and Dantrium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dantrium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dantrium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and dantrolene sodium (the active ingredients of Lorazepam and Dantrium, respectively), and Lorazepam and Dantrium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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