Lorazepam and Estropipate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lorazepam (lorazepam) and Estropipate (estropipate). Common drug interactions include delirium among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Lorazepam and Estropipate. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.
What is Lorazepam?
Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.
What is Estropipate?
Estropipate has active ingredients of estropipate. It is often used in hormone replacement therapy. eHealthMe is studying from 1,659 Estropipate users. Check the latest studies of Estropipate.
54 people who take Lorazepam and Estropipate together, and have interactions are studied.

What are the common drug interactions of Lorazepam and Estropipate, by gender? *:
female:
- Delirium (wild excitement)
- Malaise (a feeling of general discomfort or uneasiness)
- Mood swings (an extreme or rapid change in mood)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Diarrhoea
- Fall
- Fatigue (feeling of tiredness)
- Hepatic enzyme increased
- Hypokalaemia (low potassium)
male:
- Arthralgia (joint pain)
- Completed suicide (act of taking one's own life)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Joint swelling
- Throat irritation
What are the common drug interactions of Lorazepam and Estropipate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Joint swelling
- Throat irritation
- Arthralgia (joint pain)
- Completed suicide (act of taking one's own life)
- Dysphagia (a condition in which swallowing is difficult or painful)
40-49:
- Infection
- Sepsis (a severe blood infection that can lead to organ failure and death)
50-59:
- Asthenia (weakness)
- Chest pain
- Cholecystitis (infection of gallbladder)
- Chronic kidney disease
- Confusional state
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetes mellitus inadequate control
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Eructation (release of gas from the digestive tract)
60+:
- Confusional state
- Electrocardiogram qt prolonged
- Diarrhoea
- Fall
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
- Malaise (a feeling of general discomfort or uneasiness)
- Urinary tract infection
- Abdominal discomfort
- Blood glucose increased
- Constipation
What are the existing conditions these people have? *
- High Blood Pressure: 7 people, 12.96%
- Sleep Disorder: 6 people, 11.11%
- Pain: 6 people, 11.11%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 11.11%
- Migraine (headache): 5 people, 9.26%
- Depression: 5 people, 9.26%
- Joint Pain: 5 people, 9.26%
- Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 9.26%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 7.41%
- Hot Flush (sudden feelings of heat): 3 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Lorazepam and Estropipate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lorazepam (165,639 reports)
- Estropipate (1,659 reports)
Browse all drug interactions of Lorazepam and Estropipate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lorazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Estropipate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lorazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Estropipate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lorazepam and estropipate (the active ingredients of Lorazepam and Estropipate, respectively), and Lorazepam and Estropipate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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