Lorazepam and Gablofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorazepam (lorazepam) and Gablofen (baclofen). Common drug interactions include hypertonia among females and pancreatic carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Lorazepam and Gablofen. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Gablofen?

Gablofen has active ingredients of baclofen. eHealthMe is studying from 3,044 Gablofen users. Check the latest studies of Gablofen.



On Jul, 17, 2026

25 people who take Lorazepam and Gablofen together, and have interactions are studied.

Lorazepam and Gablofen drug interactions.

What are the common drug interactions of Lorazepam and Gablofen, by gender? *:

female:

  1. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  2. Muscular weakness (muscle weakness)
  3. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  4. Overdose
  5. Procedural nausea
  6. Procedural vomiting
  7. Device dislocation
  8. Nausea (feeling of having an urge to vomit)
  9. Pain in extremity
  10. Vomiting

male:

  1. Pancreatic carcinoma (pancreatic cancer)
  2. Confusional state
  3. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Lorazepam and Gablofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Confusional state
  2. Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

  1. Cerebrospinal fluid leakage
  2. Death
  3. Fall
  4. Implant site pain
  5. Abdominal pain
  6. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  7. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  8. Procedural nausea
  9. Procedural vomiting
  10. Nausea (feeling of having an urge to vomit)

40-49:

  1. Device failure
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Device dislocation
  4. Dyspnoea (difficult or laboured respiration)
  5. Hallucination (an experience involving the perception of something not present)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Asthenia (weakness)
  8. Confusional state
  9. Implant site infection
  10. Muscular weakness (muscle weakness)

50-59:

  1. Death
  2. Osteomyelitis (infection of bone)

60+:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Drug resistance (reduction in effectiveness of a drug)
  3. Meningitis bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  4. Pocket erosion
  5. Klebsiella test positive
  6. Lethargy (tiredness)
  7. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  8. Overdose
  9. Pathogen resistance
  10. Pseudomonas test positive

What are the existing conditions these people have? *

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 18 people, 72.00%
  2. Pain: 4 people, 16.00%
  3. Cerebral Palsy: 3 people, 12.00%
  4. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 2 people, 8.00%
  5. Spinal Cord Trauma: 2 people, 8.00%
  6. Post Laminectomy Syndrome: 2 people, 8.00%
  7. Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 2 people, 8.00%
  8. Constipation: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lorazepam and Gablofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lorazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gablofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lorazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gablofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lorazepam and baclofen (the active ingredients of Lorazepam and Gablofen, respectively), and Lorazepam and Gablofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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