Lorazepam and Hc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorazepam (lorazepam) and Hc (hydrocortisone). Common drug interactions include hypotension among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Lorazepam and Hc. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Hc?

Hc has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 1,369 Hc users. Check the latest studies of Hc.

On Jul, 28, 2026

89 people who take Lorazepam and Hc together, and have interactions are studied.

What are the common drug interactions of Lorazepam and Hc, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Arthralgia (joint pain)
Drug ineffective
Abdominal distension
Angina pectoris (chest pain due to ischemia of the heart muscle)
Bradycardia (abnormally slow heart action)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colitis ulcerative (inflammation of colon with ulcer)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)

male:

Diarrhoea
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Haemorrhage (bleeding)
Herpes zoster
Injury
Muscle spasms (muscle contraction)
Nephrolithiasis (calculi in the kidneys)
Osteomyelitis (infection of bone)
Pain
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Lorazepam and Hc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Actinic keratosis (skin disease due to sun exposure)
Acute respiratory failure
Altered state of consciousness (altered state of mind)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Atelectasis (partial or complete collapse of the lung)
Back pain
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Bladder diverticulum (pouch like projection in the bladder, by birth or acquired)
Blood pressure decreased

30-39:

Confusional state
Loss of consciousness
Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
Somnambulism (sleep walking)

40-49:

Blood potassium increased
Dysstasia (difficulty in standing)
Hospitalisation
Malaise (a feeling of general discomfort or uneasiness)
Tremor (trembling or shaking movements in one or more parts of your body)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Vomiting
Apnoea (suspension of external breathing)
Blood folate increased

50-59:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Colitis ulcerative (inflammation of colon with ulcer)
Cough
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Flatulence (flatus expelled through the anus)
Lactose intolerance (inability to digest lactose)
Renal disorder (kidney disease)
Carotid artery occlusion (artery blockage)
Hyperglycaemia (high blood sugar)

60+:

Diarrhoea
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Arthralgia (joint pain)
Drug ineffective
Thrombocytopenia (decrease of platelets in blood)
Nephrolithiasis (calculi in the kidneys)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Haemorrhage (bleeding)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

What are the existing conditions these people have? *

Pain: 29 people, 32.58%
Nausea (feeling of having an urge to vomit): 21 people, 23.60%
Depression: 12 people, 13.48%
Sleep Disorder: 12 people, 13.48%
High Blood Pressure: 9 people, 10.11%
Neoplasm Malignant (cancer tumour): 8 people, 8.99%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 8 people, 8.99%
Insomnia (sleeplessness): 8 people, 8.99%
Renal Cell Carcinoma (a kidney cancer): 7 people, 7.87%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.87%

* Approximation only. Some reports may have incomplete information.

Do you take Lorazepam and Hc?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously