Lorazepam and Nyquil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lorazepam (lorazepam) and Nyquil (acetaminophen / dextromethorphan / doxylamine / pseudoephedrine). Common drug interactions include blood pressure decreased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Lorazepam and Nyquil. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Lorazepam?

Lorazepam has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,639 Lorazepam users. Check the latest studies of Lorazepam.

What is Nyquil?

Nyquil has active ingredients of acetaminophen / dextromethorphan / doxylamine / pseudoephedrine. It is often used in cold symptoms. eHealthMe is studying from 2,240 Nyquil users. Check the latest studies of Nyquil.

On Jul, 26, 2026

78 people who take Lorazepam and Nyquil together, and have interactions are studied.

What are the common drug interactions of Lorazepam and Nyquil, by gender? *:

female:

Blood pressure decreased
Blood urea increased
Po2 increased
Respiratory rate decreased (less breathing rate/min)
Overdose
Asthma
Chest pain
Oral candidiasis (fungal infection of mouth)
Pneumonia
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)

male:

Asthenia (weakness)
Dizziness
Chills (felling of cold)
Confusional state
Dehydration (dryness resulting from the removal of water)
Depression
Diarrhoea
Drug ineffective
Haematocrit
Headache (pain in head)

What are the common drug interactions of Lorazepam and Nyquil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anorectal infection
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Fall
Febrile neutropenia (fever with reduced white blood cells)
Furuncle (infection of the hair follicle)
Lung abscess (pus in lungs)
Neuropathy peripheral (surface nerve damage)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Proctalgia (pain in the rectum)

30-39:

Depression
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Immunodeficiency
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Overdose
Paralysis
Post-traumatic stress disorder
Psychotic disorder
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

Back pain
Cardiac disorder
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Cutis laxa (connective tissue disorder in which the skin lacks elasticity and hangs in loose folds)
Delusion (a false belief or opinion)
Depression
Diarrhoea
Disturbance in attention
Dizziness
Dizziness postural

50-59:

Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Anion gap increased
Lactic acidosis (low ph in body tissues)
Loss of consciousness
Depressed level of consciousness
Analgesic drug level increased
Blood creatinine increased
Blood glucose increased
Blood lactic acid increased
Blood osmolarity increased

60+:

Asthenia (weakness)
Confusional state
Somnolence (a state of near-sleep, a strong desire for sleep)
Vertigo
White blood cell count increased
Aphasia (damage to the parts of the brain that control language)
Cardiac tamponade (fluid accumulates in heart covering)
Cellulitis (infection under the skin)
Chest pain
Chronic kidney disease

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 19.23%
Multiple Myeloma (cancer of the plasma cells): 11 people, 14.10%
Pain: 10 people, 12.82%
High Blood Pressure: 9 people, 11.54%
Cough: 9 people, 11.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 8.97%
Depression: 7 people, 8.97%
Nasopharyngitis (inflammation of the nasopharynx): 6 people, 7.69%
Erection Problems: 6 people, 7.69%
High Blood Cholesterol: 6 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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